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Merck

I3265

Interferon-γ human

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), lyophilized powder, suitable for cell culture

Synonym(s):

IFN-γ

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.32
MDL number:
Technical Service
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biological source

human

Quality Segment

recombinant

expressed in E. coli

assay

≥98% (SDS-PAGE)

form

lyophilized powder

mol wt

~17 kDa

packaging

pkg of 0.1 mg

technique(s)

cell culture | mammalian: suitable

impurities

≤1 EU/μg endotoxin

color

white

solubility

water: soluble 1.000 mL, clear, colorless

UniProt accession no.

storage temp.

−20°C

Gene Information

human ... IFNG(3458)

General description

Recombinant human Interferon-γ (IFN-γ), expressed in E. coli. ≥98% purity, endotoxin tested, lyophilized protein suitable for mammalian cell culture research.

Application

Recombinant human Interferon-γ has been used has been used in mammalian cell culture research applications, including studies on cultured trophoblasts and human gingival fibroblasts.

Biochem/physiol Actions

IFNG (interferon-γ) is a type-2 interferon which is produced by Th (T helper cells)-1 lymphocytes, CD8 cytotoxic lymphocytes, natural killer (NK) cells, and natural killer T (NKT) cells. It plays an important role in innate and adaptive immune responses, and helps in defense against bacterial infections, dimorphic yeast and some viral infections.

Physical form

Lyophilized from phosphate buffered saline.

Analysis Note

The biological activity is measured by a viral resistance assay.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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