L0664
Loxoprofen
solid
Synonym(s):
α-Methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic acid, Koloxo
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Empirical Formula (Hill Notation):
C15H18O3
CAS Number:
Molecular Weight:
246.30
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Product Name
Loxoprofen, solid
InChI
1S/C15H18O3/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16/h5-8,10,13H,2-4,9H2,1H3,(H,17,18)
SMILES string
CC(C(O)=O)c1ccc(CC2CCCC2=O)cc1
InChI key
YMBXTVYHTMGZDW-UHFFFAOYSA-N
form
solid
originator
Daiichi-Sankyo
Quality Level
Gene Information
human ... PTGS1(5742), PTGS2(5743)
Application
Anti-inflammatory; analgesic
Features and Benefits
This compound was developed by Daiichi-Sankyo. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Yasushi Kuribayashi et al.
The journal of obstetrics and gynaecology research, 43(9), 1465-1471 (2017-07-15)
We aimed to determine the frequency of endometrial cancer in infertile women undergoing hysteroscopic endometrial polypectomy for endometrial polyps. A total of 1035 infertile patients who underwent office-based hysteroscopic polypectomy at Sugiyama Clinic Marunouchi between July 2011 and October 2015
Misato Hashizume et al.
Modern rheumatology, 20(5), 432-438 (2010-04-22)
We examined the therapeutic effect of high molecular weight hyaluronic acid (HA) on the progression of joint pain and cartilage degeneration in a rabbit osteoarthritis (OA) model. The OA model was induced by partial meniscectomy. In the time course study
Teruya Komatsu et al.
International journal of surgery (London, England), 12(9), 936-939 (2014-08-06)
Appropriate postoperative analgesia is crucial in fast-track surgery, which is a multimodal therapeutic strategy that aims toward enhanced postoperative recovery and shortened hospital stay. Paravertebral block (PVB) has been reported to be as effective as thoracic epidural blockade (TEB), but
M Sugimoto et al.
Biochemical pharmacology, 42(12), 2363-2368 (1991-11-27)
The effect of loxoprofen-Na, a novel non-steroidal anti-inflammatory drug with a prodrug property, on prostaglandin (PG) levels in the inflammatory tissue was investigated with a carrageenin-induced pleurisy model in rats. The intrapleural injection of carrageenin caused a marked increase in
C Sakamoto et al.
Alimentary pharmacology & therapeutics, 37(3), 346-354 (2012-12-12)
Although nonsteroidal anti-inflammatory drugs (NSAIDs) are widely prescribed globally, their chronic use increases the risk of upper gastrointestinal (GI) damage. Cyclooxygenase-2-selective NSAIDs are considered to reduce this risk. Current guidelines in Japan recommend loxoprofen sodium (loxoprofen), a pro-drug in the
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service