434248
L-Abrine
99%
Synonym(s):
Nα-Methyl-L-tryptophan
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About This Item
Empirical Formula (Hill Notation):
C12H14N2O2
CAS Number:
Molecular Weight:
218.25
UNSPSC Code:
41116107
NACRES:
NA.22
PubChem Substance ID:
EC Number:
208-388-5
Beilstein/REAXYS Number:
86638
MDL number:
Quality Level
assay
99%
optical activity
[α]20/D +65°, c = 1 in 0.5 M NaOH
reaction suitability
reaction type: solution phase peptide synthesis
mp
>300 °C (dec.) (lit.)
application(s)
peptide synthesis
SMILES string
CN[C@@H](Cc1c[nH]c2ccccc12)C(O)=O
InChI
1S/C12H14N2O2/c1-13-11(12(15)16)6-8-7-14-10-5-3-2-4-9(8)10/h2-5,7,11,13-14H,6H2,1H3,(H,15,16)/t11-/m0/s1
InChI key
CZCIKBSVHDNIDH-NSHDSACASA-N
Biochem/physiol Actions
An indoleamino acid that shows radical scavenging and antioxidant properties in vitro.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Emilie Gauthy et al.
PloS one, 8(9), e76186-e76186 (2013-10-08)
GARP is a transmembrane protein present on stimulated human regulatory T lymphocytes (Tregs), but not on other T lymphocytes (Th cells). It presents the latent form of TGF-β1 on the Treg surface. We report here that GARP favors the cleavage
Maximilian Huber et al.
The Science of the total environment, 541, 895-919 (2015-10-09)
A dataset of 294 monitored sites from six continents (Africa, Asia, Australia, Europe, North and South America) was compiled and evaluated to characterize the occurrence and fate of heavy metals in eight traffic area categories (parking lots, bridges, and three
Huixi Zou et al.
Journal of natural products, 72(1), 44-52 (2008-12-31)
This study reports that a series of tryptophan derivatives with modifications on the side chain or at the indole ring were accepted by two cyclic dipeptide prenyltransferases, CdpNPT and FtmPT1, and converted to prenylated derivatives. The structures of the enzymatic