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Merck

H8759

4-Hydroxy-3-methoxyphenylglycol sulfate potassium salt

≥98% (HPLC), powder

Synonym(s):

(3-Methoxy-4-sulfonyloxyphenyl)glycol potassium salt, MHPG sulfate potassium salt, MOPEG sulfate potassium salt

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About This Item

Empirical Formula (Hill Notation):
C9H11KO7S
CAS Number:
71324-20-4
Molecular Weight:
302.34
UNSPSC Code:
12352200
NACRES:
NA.77
PubChem Substance ID:
24277755
MDL number:
MFCD00043417
Beilstein/REAXYS Number:
4625651
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
200

Key Documents

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InChI

1S/C9H12O7S.K/c1-15-9-4-6(7(11)5-10)2-3-8(9)16-17(12,13)14;/h2-4,7,10-11H,5H2,1H3,(H,12,13,14);/q;+1/p-1

SMILES string

[K+].COc1cc(ccc1OS([O-])(=O)=O)C(O)CO

InChI key

XFZJWBFZLNLKNR-UHFFFAOYSA-M

assay

≥98% (HPLC)

form

powder

color

off-white

solubility

H2O: 50 mg/mL

storage temp.

2-8°C

Quality Level

200

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Biochem/physiol Actions

Norepinephrine metabolite that is often used as an index of adrenergic stimulation.

Features and Benefits

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG6969
BCBM0917V
BCBM0917
262199/1
027K2513

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K W Perry et al.
Journal of neural transmission (Vienna, Austria : 1996), 104(8-9), 953-966 (1997-01-01)
The selective serotonin uptake inhibitor fluoxetine (10 mg/kg i.p.) increased tissue levels of the norepinephrine metabolite 3-methoxy-4-hydroxyphenylethylene glycol sulfate (MHPG-SO4) in rat hypothalamus, indicating an increased release of norepinephrine. Microdialysis studies in conscious rats showed that fluoxetine (10 mg/kg i.p.)
G Eisenhofer et al.
Journal of neurochemistry, 66(4), 1565-1573 (1996-04-01)
This study used regional differences in plasma concentrations of norepinephrine and its metabolites to examine how production of the transmitter by sympathetic nerves, in particular, those innervating mesenteric organs, is integrated with metabolism by the liver and elimination by the
E T Hellriegel et al.
Pharmacology, biochemistry, and behavior, 57(1-2), 207-214 (1997-05-01)
The objective of this investigation was to examine the immediate and long term effects of acute, chronic and chronic intermittent stress on the central noradrenergic system of rats. Male Sprague-Dawley rats were subjected to one hour of physical immobilization stress
Phedias Diamandis et al.
Nature chemical biology, 3(5), 268-273 (2007-04-10)
The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways that governs the

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