P3292
Pancreatin from porcine pancreas
powder, suitable for cell culture, 4 × USP specifications
Synonym(s):
Pancreatin from hog pancreas
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About This Item
Specific activity:
4 × USP specifications
Biological source:
Porcine pancreas
biological source
Porcine pancreas
agency
USP (specifications)
form
powder
specific activity
4 × USP specifications
contains
lactose or sucrose as extender (The sucrose used might contain up to 3.25% starch.)
technique(s)
cell culture | mammalian: suitable
shipped in
ambient
storage temp.
−20°C
Quality Level
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Application
Pancreatin from porcine pancreas has been used to assess the treatment of steatorrhea by lipase supplementation therapy, to investigate treatment options for pancreatic diabetes in patients experiencing the decompensated stage of chronic pancreatitis, and to safely and effectively remove formalin-fixed tissues from arterial grafts without leading to structural damage or loss in fiber integrity.
Biochem/physiol Actions
Pancreatin contains enzymatic components including trypsin, amylase and lipase, ribonuclease, and protease, produced by the exocrine cells of the porcine pancreas. This combination of enzymes allows it to hydrolyze proteins, starch and fats. Pancreatin will convert not less than 25 times its weight of potato starch into soluble carbohydrates in 5 minutes in water at 40°C, will digest not less than 25 times its weight of casein in 60 minutes at pH 7.5 at 40°C and will release not less than microequivalents of acid per min per mg pancreatin from olive oil at pH 9.0 at 37°C.
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 1
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Xu-Dong Kong et al.
Nature biomedical engineering, 4(5), 560-571 (2020-05-13)
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The Biochemical journal, 478(11), 2059-2079 (2021-05-19)
Insulin and insulin-like growth factor stimulate protein synthesis and cardioprotection in the heart, acting through their receptors (INSRs, IGF1Rs) and signalling via protein kinase B (PKB, also known as Akt). Protein synthesis is increased in hearts perfused at alkaline pHo
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Antioxidants (Basel, Switzerland), 9(12) (2020-12-24)
Bioactive peptides are a group of molecules with health beneficial properties, deriving from food matrices. They are protein fragments consisting of 2-20 amino acids that can be released by microbial fermentation, food processing and gastrointestinal digestion. Once hydrolyzed from their
C Giromini et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 34(8), 1436-1445 (2017-04-12)
Ex-food or former food products (FFPs) have been proposed as one of the categories with great promise as alternative feed ingredients. FFPs' nutritional potential is not yet fully exploited. Therefore, the aim of this study was to perform a nutritional
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