1.02975
Sorbitol
FP, liquid, (sorbitol syrup, noncrystallizing), EMPROVE® ESSENTIAL, Ph. Eur., BP, NF, E 420
Synonym(s):
D-Sorbitol, Sorbit, Sorbitol, Sionon, Sorbo, D-Glucitol
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About This Item
Empirical Formula (Hill Notation):
C6H14O6
CAS Number:
Molecular Weight:
182.17
E Number:
E420
UNSPSC Code:
12352104
Beilstein/REAXYS Number:
1721899
MDL number:
Quality Level
agency
BP, NF, Ph. Eur.
vapor density
<1 (vs air)
vapor pressure
<0.1 mmHg ( 25 °C)
product line
EMPROVE® ESSENTIAL
form
liquid, viscous liquid
pH
6 (20 °C in H2O, 50% solution)
mp
98-100 °C (lit.)
density
1.3 g/cm3 at 20 °C
application(s)
liquid formulation
pharmaceutical
storage temp.
2-30°C
SMILES string
OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO
InChI
1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1
InChI key
FBPFZTCFMRRESA-JGWLITMVSA-N
General description
Whether suspensions, emulsions or solutions – oral liquid dosage forms offer a number of advantages: They allow for individual dosing, are easy to swallow and are suitable for pediatric or geriatric applications. On the other hand, formulators face considerable challenges concerning solubility, API stability in aqueous systems, or taste that can often make a decisive difference. Our large product portfolio covers all excipients required for oral liquid formulation, as solvents and surfactants, flavors, ph adjustments and buffers, preservatives and viscosity enhancers.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.
Application
Sorbitol is a sugar alcohol which is frequently used as sweetener in oral liquid pharmaceutical formulations, as well as bulking agent, sugar substitute or humectant in cosmetics and food and beverage. Non-crystallizing sorbitol is especially used as humectant and plasticizer for soft-gel capsules.
Legal Information
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
10 - Combustible liquids
wgk
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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