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Merck

35837

4-Aminophenol

PESTANAL®, analytical standard

Synonym(s):

4-Hydroxyaniline

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About This Item

Linear Formula:
H2NC6H4OH
CAS Number:
123-30-8
Molecular Weight:
109.13
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329755229
EC Number:
204-616-2
Beilstein/REAXYS Number:
385836
MDL number:
MFCD00007869

Key Documents

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grade

analytical standard

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

185-189 °C (lit.)

solubility

water: slightly soluble

application(s)

agriculture
environmental

format

neat

SMILES string

Nc1ccc(O)cc1

InChI

1S/C6H7NO/c7-5-1-3-6(8)4-2-5/h1-4,8H,7H2

InChI key

PLIKAWJENQZMHA-UHFFFAOYSA-N

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General description

4-Aminophenol can be obtained via the reduction of 4-nitrophenol with excess of sodium borohydride. It can also be obtained as a primary hydrolytic degradation product of paracetamol.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Warning

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Muta. 2 - Skin Sens. 1 - STOT RE 2

target_organs

Kidney

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP3742
BCCP0499
BCCL6158
BCCL0921
BCCL2744

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Reduction of 4-nitrophenol to 4-aminophenol over Au nanoparticles deposited on PMM
Kuroda K, et al.
J. Mol. Catal. A: Chem., 298, 7-11 (2009)
A sensitive and rapid assay for 4-aminophenol in paracetamol drug and tablet formulation, by flow injection analysis with spectrophotometric detection
Bloomfield.S.M
Talanta, 58, 1301-1310 (2002)
Y Xu et al.
Clinical chemistry, 36(11), 1941-1944 (1990-11-01)
A sandwich-type heterogeneous enzyme immunoassay with flow-injection analysis for alpha-fetoprotein (AFP) in human serum has been developed. 4-Aminophenol, the product of enzymatic reaction, is detected amperometrically. The interassay CV for this electrochemical enzyme immunoassay was less than 8.2%, with a
Tomoyuki Yasukawa et al.
Biosensors & bioelectronics, 37(1), 19-23 (2012-05-23)
In this work, a novel immunosensing method has been developed on the basis of the sensitive determination of a product generated by an enzyme reaction with dual amplification system combining an electrochemical-redox cycling and coulometric signal transduction using a galvanic
Chengzhou Zhu et al.
Nanoscale, 3(10), 4376-4382 (2011-09-10)
In this paper, we reported a simple, aqueous-phase route to the synthesis of two-dimensional graphene/SnO(2) composite nanosheets (GSCN) hybrid nanostructures consisting of 5 nm Pt nanoparticles supported on the both sides of GSCN. Functional two-dimensional GSCN were obtained through the
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