93893
Physcion
analytical standard
Synonym(s):
1,8-Dihydroxy-3-methoxy-6-methylanthraquinone, 6-O-Methylemodin, 6-Methoxychrysophanic acid, Emodin-3-methyl ether, Parietin, Rheochrysidin
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About This Item
Empirical Formula (Hill Notation):
C16H12O5
CAS Number:
Molecular Weight:
284.26
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
208-315-7
Beilstein/REAXYS Number:
6770499
MDL number:
grade
analytical standard
Quality Level
assay
≥98.0% (HPLC)
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
food and beverages
format
neat
storage temp.
2-8°C
SMILES string
COc1cc(O)c2C(=O)c3c(O)cc(C)cc3C(=O)c2c1
InChI
1S/C16H12O5/c1-7-3-9-13(11(17)4-7)16(20)14-10(15(9)19)5-8(21-2)6-12(14)18/h3-6,17-18H,1-2H3
InChI key
FFWOKTFYGVYKIR-UHFFFAOYSA-N
General description
Physcion is an anthraquinone derivative and is available as the active constituent of Chinese medicinal plants such as Rhubarb, Polygonum cuspidatum and Reynoutria multiflora. It exhibits various biological activities such as antitumor, antimicrobial, antifungal, antioxidant and antihuman cytomegalovirus activity.
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Physcion may be used as an analytical reference standard for the quantification of the analyte in medicinal plants, pharmaceutical preparations, vegetables, herbs and liquors using different chromatography techniques.
Biochem/physiol Actions
Anthraquinone-derivative found in medicinal herbs.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Occurrence of emodin, chrysophanol and physcion in vegetables, herbs and liquors. Genotoxicity and anti-genotoxicity of the anthraquinones and of the whole plants
Mueller O.S, et al.
Food And Chemical Toxicology, 37(5), 481-491 (1999)
Zhenli Liu et al.
Planta medica, 77(16), 1855-1860 (2011-06-16)
The dried roots of Polygonum multiflorum Thunb. (Heshouwu) and their processed products (Zhi-heshouwu) are widely used in traditional Chinese medicine, yet their therapeutic effects are different. Previous investigations focused mainly on the differences between Heshouwu and Zhi-heshouwu in the contents
Henning Hopf et al.
Acta crystallographica. Section C, Crystal structure communications, 68(Pt 8), o317-o319 (2012-08-02)
The structure of the title compound, 7-methoxy-2-methyl-4,5-dihydroxyanthracene-9,10-dione, C(16)H(12)O(5), was originally reported by Ulický et al. [Acta Cryst. (1991). C47, 1879-1881] in the space group P2(1)2(1)2(1) [polymorph (Io)]. The new polymorph, (Im), crystallizes in the space group P2(1)/c. The molecular structures