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Merck

K3752

α-Ketoglutaric acid disodium salt hydrate

≥95%

Synonym(s):

2-Oxopentanedioic acid disodium salt hydrate, Sodium 2-oxoglutarate dibasic hydrate

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About This Item

Linear Formula:
C5H4O5Na2· xH2O
CAS Number:
305-72-6
Molecular Weight:
190.06 (anhydrous basis)
NACRES:
NA.24
PubChem Substance ID:
329817140
UNSPSC Code:
41116107
MDL number:
MFCD00150702

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InChI

1S/C5H6O5.2Na.2H2O/c6-3(5(9)10)1-2-4(7)8;;;;/h1-2H2,(H,7,8)(H,9,10);;;2*1H2/q;2*+1;;/p-2

SMILES string

O.O.[Na+].[Na+].[O-]C(=O)CCC(=O)C([O-])=O

InChI key

HSSWOFWCOAQLHZ-UHFFFAOYSA-L

grade

analytical standard

assay

≥95%

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

2-8°C

Quality Level

100

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH6436
BCCH3767
BCCG0336
BCCC3217
BCBV1061

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Won Dong Lee et al.
Nature communications, 10(1), 1351-1351 (2019-03-25)
The inability to inspect metabolic activities within subcellular compartments has been a major barrier to our understanding of eukaryotic cell metabolism. Here, we describe a spatial-fluxomics approach for inferring metabolic fluxes in mitochondria and cytosol under physiological conditions, combining isotope
Ricardo Alves da Rocha et al.
Biochemistry, 52(15), 2683-2693 (2013-03-23)
PII proteins are important regulators of nitrogen metabolism in a wide variety of organisms: the binding of the allosteric effectors ATP, ADP, and 2-oxoglutarate (2-OG) to PII proteins affects their ability to interact with target proteins. We modeled the simultaneous
D Esser et al.
Extremophiles : life under extreme conditions, 17(2), 205-216 (2013-01-09)
Aldehyde dehydrogenases (ALDHs) have been well established in all three domains of life and were shown to play essential roles, e.g., in intermediary metabolism and detoxification. In the genome of Sulfolobus solfataricus, five paralogs of the aldehyde dehydrogenases superfamily were
Kenji Manabe et al.
Microbial cell factories, 12, 18-18 (2013-02-20)
The Bacillus subtilis genome-reduced strain MGB874 exhibits enhanced production of exogenous extracellular enzymes under batch fermentation conditions. We predicted that deletion of the gene for RocG, a bi-functional protein that acts as a glutamate dehydrogenase and an indirect repressor of
N A Smirnova et al.
Biochemistry. Biokhimiia, 77(10), 1108-1119 (2012-11-20)
This review describes the catalytic mechanism, substrate specificity, and structural peculiarities of alpha-ketoglutarate dependent nonheme iron dioxygenases catalyzing prolyl hydroxylation of hypoxia-inducible factor (HIF). Distinct localization and regulation of three isoforms of HIF prolyl hydroxylases suggest their different roles in
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