H7891
Hexammine cobalt(III) chloride
for use in transformations, X-ray crystallography and NMR
Synonym(s):
Cobalt hexammine trichloride, Hexaamminecobalt trichloride
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About This Item
Linear Formula:
[Co(NH3)6]Cl3
CAS Number:
Molecular Weight:
267.48
NACRES:
NA.52
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
234-103-9
MDL number:
grade
Molecular Biology
Quality Level
form
powder
storage temp.
room temp
SMILES string
N.N.N.N.N.N.[Cl-].[Cl-].[Cl-].[Co+3]
InChI
1S/3ClH.Co.6H3N/h3*1H;;6*1H3/q;;;+3;;;;;;/p-3
InChI key
JXBGZYGSWFSYFI-UHFFFAOYSA-K
General description
Hexammine cobalt(III) is considered an analog of fully solvated magnesium, capable of activating some enzymes that requires magnesium. It is useful in DNA condensation studies.
Application
Suitable for
- DNA condensation studies
- induction of transitions of DNA from B to A or Z forms
- induction of nucleic acid crystal growth
- stabilization of tertiary tRNA interactions
- preparation of ligation buffer
signalword
Danger
hcodes
Hazard Classifications
Aquatic Chronic 4 - Carc. 2 - Resp. Sens. 1 - Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Filip Senigl et al.
Cell reports, 29(12), 3902-3915 (2019-12-19)
Somatic hypermutation (SHM) introduces point mutations into immunoglobulin (Ig) genes but also causes mutations in other parts of the genome. We have used lentiviral SHM reporter vectors to identify regions of the genome that are susceptible ("hot") and resistant ("cold")
HCC ligation: rapid and specific DNA construction with blunt ended DNA fragments.
J A Murray
Nucleic acids research, 14(24), 10118-10118 (1986-12-22)
B Grünewald
The Journal of comparative neurology, 404(1), 114-126 (1999-01-14)
The anatomy of gamma-aminobutyric acid (GABA)-immunoreactive, recurrent feedback neurons in the mushroom body (MB) of the honeybee, Apis mellifera, was investigated by using intraneuropilar injections of cobalt ions and light microscopic techniques. Each MB contains approximately 110 GABA-immunoreactive neurons, and