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Merck

L9625

Leu-Gly

≥98% (TLC)

Synonym(s):

Leucylglycine

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About This Item

Empirical Formula (Hill Notation):
C8H16N2O3
CAS Number:
Molecular Weight:
188.22
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
211-688-9
MDL number:
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Product Name

Leu-Gly,

assay

≥98% (TLC)

Quality Level

form

powder

color

white

storage temp.

−20°C

SMILES string

CC(C)C[C@H](N)C(=O)NCC(O)=O

InChI

1S/C8H16N2O3/c1-5(2)3-6(9)8(13)10-4-7(11)12/h5-6H,3-4,9H2,1-2H3,(H,10,13)(H,11,12)/t6-/m0/s1

InChI key

LESXFEZIFXFIQR-LURJTMIESA-N

Biochem/physiol Actions

Leucylglycine (Leu-Gly) is used to study the kinetics and speciation of copper(II)- cis, cis-1,3,5-triaminocyclohexane complex-promoted hydrolysis of dipeptides.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Cleavage of L-leucine-containing dipeptides by Clostridium butyricum.
Khelifa N, Brik M, Tessedre AC, et al.
Bioorganic & Medicinal Chemistry, 9, 109-112 (1999)
Yuki Fujii et al.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 7(7-8), 843-851 (2002-08-31)
The hydrolysis of glycylglycine (GylGly), glycyl-L-leucine (GlyLeu), L-leucylglycine (LeuGly) and glycyl-DL-serine (GlySer) promoted by a copper(II)- cis, cis-1,3,5-triaminocyclohexane complex [Cu(II)TACH] was investigated at 70 degrees C and pH 7-10, using HPLC. The observed pseudo-first-order rate constants (k(obs)) and rate enhancing
Irene L Gutiérrez et al.
Molecular neurobiology, 55(10), 7872-7885 (2018-02-27)
The decline in brain noradrenaline levels is associated with the progression of certain neurodegenerative diseases. This seems to be due, at least in part, to the ability of noradrenaline to limit glial activation and to reduce the damage associated with