240230
Phthalimide
≥99%
Synonym(s):
1,3-Dihydro-1,3-dioxoisoindole
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About This Item
Empirical Formula (Hill Notation):
C8H5NO2
CAS Number:
Molecular Weight:
147.13
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
201-603-3
Beilstein/REAXYS Number:
118522
MDL number:
Assay:
≥99%
InChI key
XKJCHHZQLQNZHY-UHFFFAOYSA-N
InChI
1S/C8H5NO2/c10-7-5-3-1-2-4-6(5)8(11)9-7/h1-4H,(H,9,10,11)
SMILES string
O=C1NC(=O)c2ccccc12
assay
≥99%
Quality Level
solubility
water: slightly soluble(lit.)
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Application
Phthalimide was used in the synthesis of 6-amino agarose (AA) by Mitsunobu-inspired microwave mediated method.
wgk
WGK 1
flash_point_f
302.0 °F - closed cup
flash_point_c
150 °C - closed cup
ppe
Eyeshields, Gloves, type N95 (US)
Storage Class
11 - Combustible Solids
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Alessio Pierini et al.
Journal of veterinary science, 21(5), e60-e60 (2020-10-06)
Tumor-associated neoangiogenesis is a crucial target for antitumor therapies. Thalidomide (TAL) is a promising anti-neoangiogenetic drug that has recently been used in the treatment of several malignancies in dogs. The aim of the study was to assess the pharmacokinetics of
Stalin Kondaveeti et al.
Carbohydrate polymers, 106, 365-373 (2014-04-12)
A facile 6-aminoagarose (AA) mediated synthesis of new fluorogenic amides of agarose with nicotinic (AA-NA) and picolinic acids (AA-PA) employing carbodiimide chemistry have been described. 6-Amino agarose (AA) was synthesized in a facile Mitsunobu-inspired microwave mediated method involving the reaction
Ive Hermans et al.
Physical chemistry chemical physics : PCCP, 10(8), 1125-1132 (2008-02-14)
Abstraction of hydrogen atoms by pthalimide-N-oxyl radicals is an important step in the N-hydroxyphthalimide catalyzed autoxidation of hydrocarbons. In this contribution, the temperature dependency of this reaction is evaluated by a detailed transition state theory based kinetic analysis for the
Edward C Lawson et al.
Journal of medicinal chemistry, 52(23), 7432-7445 (2009-09-08)
We have discovered two related chemical series of nonpeptide urotensin-II (U-II) receptor antagonists based on piperazino-phthalimide (5 and 6) and piperazino-isoindolinone (7) scaffolds. These structure types are distinctive from those of U-II receptor antagonist series reported in the literature. Antagonist
Shi Tang et al.
Organic letters, 10(6), 1179-1182 (2008-02-23)
A novel palladium-catalyzed intermolecular aminopalladation/C-H activation method for selectively synthesizing (E)-(2-oxindolin-3-ylidene)phthalimides has been developed. In the presence of Pd(OAc)2 and PhI(OAc)2, alkynes were difunctionalized with a phthalimide and an arene sp2 C-H bond to selectively synthesize (E)-(2-oxoindolin-3-ylidene)phthalimides, which products are
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