PHR1338
Triclosan
Pharmaceutical Secondary Standard; Certified Reference Material
Synonym(s):
Triclosan, 5-Chloro-2-(2,4-dichlorophenoxy)phenol, Irgasan
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C12H7Cl3O2
CAS Number:
Molecular Weight:
289.54
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
222-182-2
Beilstein/REAXYS Number:
2057142
MDL number:
Quality Segment
grade
certified reference material, pharmaceutical secondary standard
agency
traceable to USP 1682206
API family
triclosan
CofA
current certificate can be downloaded
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-30°C
SMILES string
Oc1cc(Cl)ccc1Oc2ccc(Cl)cc2Cl
InChI
1S/C12H7Cl3O2/c13-7-1-3-11(9(15)5-7)17-12-4-2-8(14)6-10(12)16/h1-6,16H
InChI key
XEFQLINVKFYRCS-UHFFFAOYSA-N
General description
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards.
Triclosan is a non-ionic broad spectrum antibacterial and antifungal agent, used in personal care products such as antiseptic soaps, toothpastes, fabrics and plastics.
Triclosan is a non-ionic broad spectrum antibacterial and antifungal agent, used in personal care products such as antiseptic soaps, toothpastes, fabrics and plastics.
Application
Triclosan may be used as a pharmaceutical reference standard for the determination of the analyte in waste water samples and food stuffs by various chromatography methods.
A component of cefsulodin-irgasan-novobiocin selection medium for Yersinia, a human pathogen that may contaminate animal-source food products.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Biochem/physiol Actions
It is an inhibitor of the enoyl-ACP (acyl-carrier protein) reductase component of type II fatty acid synthase (FAS-II) in bacteria and Plasmodium. It also inhibits mammalian fatty acid synthase (FASN), and may have anticarcinogenic activity.
Analysis Note
These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA9502 in the slot below. This is an example certificate only and may not be the lot that you receive.
Still not finding the right product?
Explore all of our products under Triclosan
signalword
Warning
hcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.