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Merck

P6636

L-α-Phosphatidylinositol from Glycine max (soybean)

~50% (TLC)

Synonym(s):

1,2-Diacyl-sn-glycero-3-phospho-(1-D-myo-inositol), Afamelanotide

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About This Item

CAS Number:
UNSPSC Code:
12352211
NACRES:
NA.25
EC Number:
306-553-7
Beilstein/REAXYS Number:
8535268
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biological source

soybean

Quality Level

form

crude powder

concentration

~50% (TLC)

functional group

phospholipid

lipid type

phosphoglycerides

shipped in

ambient

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)O[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]1O)OC(=O)CCCCCCCCCCCCCCCCC

InChI

1S/C45H87O13P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(46)55-35-37(36-56-59(53,54)58-45-43(51)41(49)40(48)42(50)44(45)52)57-39(47)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h37,40-45,48-52H,3-36H2,1-2H3,(H,53,54)/t37-,40?,41-,42+,43-,44-,45?/m1/s1

InChI key

FQZQXPXKJFOAGE-KAEDGTSCSA-N

Biochem/physiol Actions

Phospholipid membrane component, precursor of inositol phosphates.

Analysis Note

May contain phosphatidic acid and phosphatidyl ethanolamine


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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T Chakraborty et al.
Journal of bacteriology, 174(2), 568-574 (1992-01-01)
The prfA gene of Listeria monocytogenes encodes a protein that activates transcription of the listeriolysin gene (lisA). In order to explore the role of the prfA gene product in the pathogenesis of listerial infection, we constructed a site-directed insertion mutation
Qiangjun Zhou et al.
Nature communications, 5, 3552-3552 (2014-03-29)
Phosphatidylinositol 4-kinase IIα (PI4KIIα), a membrane-associated PI kinase, plays a central role in cell signalling and trafficking. Its kinase activity critically depends on palmitoylation of its cysteine-rich motif (-CCPCC-) and is modulated by the membrane environment. Lack of atomic structure
Tamar Burg-Golani et al.
Journal of bacteriology, 195(23), 5262-5272 (2013-09-24)
Listeria monocytogenes is a Gram-positive human intracellular pathogen that infects diverse mammalian cells. Upon invasion, L. monocytogenes secretes multiple virulence factors that target host cellular processes and promote infection. It has been presumed, but was not empirically established, that the