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204910 Complement C9, Human

204910
Purchase on Sigma-Aldrich

Descripción

Replacement Information

Products

Número de referenciaEmbalaje Cant./Env.
204910-250UG Ampolla de plást. 250 μg
Description
OverviewNative, human C9 complement component. Single-chain glycoprotein present in normal human serum at 60 µg/ml. On activation of complement via either the classical or alternative pathway, formation of the C5b fragment initiates assembly of the C5b-9 complement membrane attack complex (MAC) on target surfaces. Full lytic activity of MAC occurs only after binding of three to six C9 molecules to each C5b-8 complex.
Catalogue Number204910
Brand Family Calbiochem®
References
ReferencesStanley, K.K., et al. 1985. EMBO J. 4, 375.
Biesecker, G. and Muller-Eberhard, H.J. 1980. J. Immunol. 124, 1291.
Product Information
CAS number80295-59-6, 7778-77-0, 10028-24-7, 7447-40-7, 7647-14-5
FormLiquid
FormulationIn PBS, pH 7.2, filtered through a 0.22 µm pore size filter.
Quality LevelMQ200
Applications
Biological Information
Purity≥95% by SDS-PAGE
SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Specific Activity≥150,000 C9H50 units/mg
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
ContaminantsIgG, IgA, IgM, albumin, C3, C4, C5, C6, C7, or C8: ≤trace amounts
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Complement C9, Human Ficha datos de seguridad (MSDS)

Título

Ficha técnica de seguridad del material (MSDS) 

Complement C9, Human Certificados de análisis

CargoNúmero de lote
204910

Referencias bibliográficas

Visión general referencias
Stanley, K.K., et al. 1985. EMBO J. 4, 375.
Biesecker, G. and Muller-Eberhard, H.J. 1980. J. Immunol. 124, 1291.
Ficha técnica

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision27-May-2008 RFH
DescriptionNative, human C9 complement component. Single-chain glycoprotein present in normal human serum at 60 µg/ml. On activation of complement via either the classical or alternative pathway, formation of the C5b fragment initiates assembly of C5b-9 complement membrane attack complex (MAC) on target surfaces. Full lytic activity of MAC occurs only after binding of three to six C9 molecules to each C5b-8 complex.
FormLiquid
FormulationIn PBS, pH 7.2, filtered through a 0.22 µm pore size filter.
Concentration Label Please refer to vial label for lot-specific concentration
SourcePrepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
CAS number80295-59-6, 7778-77-0, 10028-24-7, 7447-40-7, 7647-14-5
Purity≥95% by SDS-PAGE
ContaminantsIgG, IgA, IgM, albumin, C3, C4, C5, C6, C7, or C8: ≤trace amounts
Specific activity≥150,000 C9H50 units/mg
Storage ≤ -70°C
Avoid freeze/thaw
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Toxicity Standard Handling
ReferencesStanley, K.K., et al. 1985. EMBO J. 4, 375.
Biesecker, G. and Muller-Eberhard, H.J. 1980. J. Immunol. 124, 1291.