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341006 EDAC, Hydrochloride

341006
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

CAS #Purity
25952-53-8≥98% by Titration

Products

Catalogue NumberPackaging Qty/Pack
341006-25GM Glass bottle 25 gm
341006-5GM Plastic ampoule 5 gm
Description
OverviewWater-soluble carbodiimide derivative. Used to modify NMDA receptors. Also useful for conjugating haptens to proteins or polypeptides.
Molar absorptivity (~212 nm; 50 mM phosphate buffer, pH 8):≥6800 M-1cm-1.
Catalogue Number341006
Brand Family Calbiochem®
SynonymsEDCI, 1-Ethyl-3-(3ʹ-dimethylaminopropyl)carbodiimide, HCl
References
ReferencesChazot, P.L., et al. 1993. Biochem. Pharmacol. 45, 605.
Richardson, A., et al. 1992. Biochem. Pharmacol. 43, 1415.
Taniuchi, M., et al. 1986. Proc. Natl. Acad. Sci. USA 83, 1950.
Chase, J.W., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 5480.
Williams, A., et al. 1981. J. Am. Chem. Soc. 103, 7090.
Yamada, H., et al. 1981. Biochemistry 20, 4836.
Thomas, J.O., et al. 1978. J. Mol. Biol. 123, 149.
Ozawa, H. 1970. Biochemistry 9, 2158.
Kopple, K.D., et al. 1962. J. Am. Chem. Soc. 84, 4457.
Product Information
CAS number25952-53-8
FormWhite solid
Hill FormulaC₈H₁₇N₃ · HCl
Chemical formulaC₈H₁₇N₃ · HCl
Hygroscopic Hygroscopic
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
Biological Information
Purity≥98% by Titration
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSFF2200000
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage -20°C
Protect from Moisture Protect from moisture
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsUnstable in solution. Reconstitute just prior to use.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications

Documentation

EDAC, Hydrochloride SDS

Title

Safety Data Sheet (SDS) 

EDAC, Hydrochloride Certificates of Analysis

TitleLot Number
341006

References

Reference overview
Chazot, P.L., et al. 1993. Biochem. Pharmacol. 45, 605.
Richardson, A., et al. 1992. Biochem. Pharmacol. 43, 1415.
Taniuchi, M., et al. 1986. Proc. Natl. Acad. Sci. USA 83, 1950.
Chase, J.W., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 5480.
Williams, A., et al. 1981. J. Am. Chem. Soc. 103, 7090.
Yamada, H., et al. 1981. Biochemistry 20, 4836.
Thomas, J.O., et al. 1978. J. Mol. Biol. 123, 149.
Ozawa, H. 1970. Biochemistry 9, 2158.
Kopple, K.D., et al. 1962. J. Am. Chem. Soc. 84, 4457.

Brochure

Title
Excitotoxic Glutamate Analogs Technical Bulletin
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision17-October-2017 JSW
SynonymsEDCI, 1-Ethyl-3-(3ʹ-dimethylaminopropyl)carbodiimide, HCl
DescriptionWater-soluble derivative of carbodiimide useful for conjugating haptens to proteins and polypeptides. Used to modify NMDA receptors and as a condensing agent in peptide synthesis. The major advantage of EDAC coupling is the easy removal of excess reagent and the corresponding urea by washing with dilute acid or water. Carbodiimides catalyze the formation of amide bonds, carboxylic acids, and amines by activating the carboxylate to form an O-acylurea. This intermediate can be attacked by an amine directly to form an amide. EDAC is released as a soluble urea derivative.
FormWhite solid
Intert gas (Yes/No) Packaged under inert gas
CAS number25952-53-8
RTECSFF2200000
Chemical formulaC₈H₁₇N₃ · HCl
Structure formulaStructure formula
Purity≥98% by Titration
SolubilityH₂O (2-5 mg/ml) or Aqueous buffers (2-5 mg/ml). Avoid amine containing buffers.
Storage -20°C
Hygroscopic
Protect from moisture
Do Not Freeze Ok to freeze
Special InstructionsUnstable in solution. Reconstitute just prior to use.
Toxicity Irritant
ReferencesChazot, P.L., et al. 1993. Biochem. Pharmacol. 45, 605.
Richardson, A., et al. 1992. Biochem. Pharmacol. 43, 1415.
Taniuchi, M., et al. 1986. Proc. Natl. Acad. Sci. USA 83, 1950.
Chase, J.W., et al. 1983. Proc. Natl. Acad. Sci. USA 80, 5480.
Williams, A., et al. 1981. J. Am. Chem. Soc. 103, 7090.
Yamada, H., et al. 1981. Biochemistry 20, 4836.
Thomas, J.O., et al. 1978. J. Mol. Biol. 123, 149.
Ozawa, H. 1970. Biochemistry 9, 2158.
Kopple, K.D., et al. 1962. J. Am. Chem. Soc. 84, 4457.