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Merck

1.52023

Chromolith® HighResolution RP-18 endcapped (monolithic) HPLC Columns

L × I.D.150 mm x 4.6 mm HPLC Column

Synonym(s):

Chromolith® HighResolution RP-18 endcapped 150-4.6 HPLC column

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About This Item

UNSPSC Code:
41115700
NACRES:
SB.52
Matrix active group:
C18 bonding phase, octadecylsilane (ODS), C18 bonding phase
Pore size:
1.15 μm macroporosity, 1.5 μm macroporosity, 15 nm mesoporosity
Matrix:
highly porous, monolithic silica
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Product Name

Chromolith® HighResolution RP-18 endcapped, L × I.D.150 mm x 4.6 mm HPLC column

material

PEEK column

Quality Level

agency

suitable for USP L1

product line

Chromolith®

feature

endcapped

packaging

1 ea of

extent of labeling

15% Carbon loading, 18% Carbon loading

parameter

200 bar pressure, 45 °C max. temp., 50 °C max. temp.

technique(s)

HPLC: suitable, LC/MS: suitable, mass spectrometry (MS): suitable (High)

column L × I.D.

15 cm × 4.6 mm

surface area

250 m2/g × 250 m2/g

matrix

highly porous, monolithic silica

matrix active group

C18 bonding phase, octadecylsilane (ODS), C18 bonding phase

pore size

1.15 μm macroporosity, 1.5 μm macroporosity, 15 nm mesoporosity

operating pH range

2-7.5

separation technique

reversed phase

storage temp.

no temp limit

General description

Chromolith® columns are made of monolithic silica with a characteristic bimodal pore structure.

Chromolith® HighResolution RP-18 endcapped columns have macropores with 1.15 μm diameter, giving a column efficiency exceeding 140,000 plates/meter. The mesopores are 15 nm (150 Å), the surface modification is octadecylsilane with full end-capping.

Chromolith® HighResolution RP-18 endcapped columns fall under the USP L1 Classification. The column efficiency is comparable to a 2.7 to 3 μm particle size fully porous particulate column. Chromolith® HighResolution RP-18 endcapped columns are perfectly suitable for LC-MS applications.
The column dimension of 150 mm length and 4.6 mm I.D. is the best choice for high-resolution separations of complex compound mixtures on any HPLC System.

The revolutionary, monolithic silica with its unique combination of macropores and mesopores enables:
—Rapid separations at very low column back-pressure
—High matrix tolerance, allowing time and cost savings with simplified workflows
—Cost-savings due to extended column lifetimes
—Connection of columns, flow gradients and the use of mobile phases with higher viscosity

The recommended Guard-columns are:
Chromolith® HighResolution RP-18 endcapped 5-4.6 guard cartridges (3 pieces) [1.52025]
with the Chromolith® Guard Cartridge Holder 5 mm x 4.6 mm [1.52032]
The Chromolith® column coupler can be used to significantly increase the separation efficiency of Chromolith® columns by coupling several columns in series (up to 100,000 plates/per column). [1.51467]

Learn more:
Brochure: Race through your Separations on Any System. Chromolith® Monolithic Silica HPLC Columns

All Supelco HPLC Columns, including monolithic Chromolith® columns, are fully compatible to all HPLC and UHPLC Instruments.
Supelco HPLC Products: The Best Choice for Any LC Instrument

Chromolith® HighResolution RP-18 endcapped columns are also available in 2 mm I.D. column dimension for perfect fit to UHPLC and UHPLC-MS needs.
Flyer: UHPLC-like performance - Rapid and Robust at Low Pressure - Chromolith® HighResolution RP-18 endcapped 2 mm I.D. HPLC Columns

Legal Information

Chromolith is a registered trademark of Merck KGaA, Darmstadt, Germany


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Storage Class

11 - Combustible Solids



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