8.20171
Bromine
for synthesis
Synonym(s):
Bromine
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
CAS Number:
Molecular Weight:
159.81
UNSPSC Code:
12352300
EC Index Number:
231-778-1
NACRES:
NA.22
MDL number:
Form:
liquid
vapor pressure
233 hPa ( 20 °C)
Quality Level
form
liquid
reaction suitability
reagent type: oxidant
kinematic viscosity
0.314 cSt(20 °C)
bp
58.8 °C/1013 hPa
mp
-7.3 °C
solubility
35 g/L
density
3.12 g/cm3 at 20 °C (liquid)
storage temp.
15-25°C
SMILES string
[Br-]
InChI
1S/BrH/h1H/p-1
InChI key
CPELXLSAUQHCOX-UHFFFAOYSA-M
General description
for synthesis
Application
Bromine can be used as an oxidizing agent for the oxidation of:
Bromine can also be used along with other co-reactants such as hexamethylphosphoric triamide (HMPA) and bis(tributyltin) oxide (HBD) to selectively oxidize secondary alcohols. However, bromine/nickel carboxylates convert 1,4-diols to γ-butyrolactones by selective oxidation of the primary alcohols.
- Primary alcohols to either aldehydes or esters and secondary alcohols to give ketones.
- Alcohols or diols to tetrahydrofurans in the presence of silver(I) salts.
- Enediol bis-trimethylsilyl ethers to α-diketones.
- Aldehydes to esters in the presence of alcohol solvents and sodium bicarbonate buffer.
- Aliphatic and aromatic thiols to disulfides.
Bromine can also be used along with other co-reactants such as hexamethylphosphoric triamide (HMPA) and bis(tributyltin) oxide (HBD) to selectively oxidize secondary alcohols. However, bromine/nickel carboxylates convert 1,4-diols to γ-butyrolactones by selective oxidation of the primary alcohols.
Analysis Note
Assay (iodometric)≥ 99.0 %AppearanceBrownish-red fuming liquid
Still not finding the right product?
Explore all of our products under Bromine
signalword
Danger
Hazard Classifications
Acute Tox. 1 Inhalation - Aquatic Acute 1 - Eye Dam. 1 - Skin Corr. 1A
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
hcodes
Storage Class
6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Bromine as an oxidant for direct conversion of aldehydes to esters
Williams DR, et al.
Tetrahedron Letters, 29(40) (1988)
Bromine
Goehring RR
eEROS (Encyclopedia of Reagents for Organic Synthesis) (2001)
Preparation of disulfides by the oxidation of thiols using bromine
Wu Xiaoming, et al.
Synthetic Communications, 26(1) (1996)