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Merck

C1022

Carmine

≥42.0% purity, powder

Synonym(s):

Alum lake of carminic acid, Cochineal, Nacarat, Natural Red 4

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12171500
NACRES:
NA.47
EC Number:
215-724-4
Colour Index Number:
75470
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Product Name

Carmine, powder, ≥42.0% (UV-vis)

Quality Level

assay

≥42.0% (UV-vis)

form

powder

color

red

solubility

ammonium hydroxide: 1 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

O1C(C(C(C(C1c2c(c3c(c(c2O)O)C(=O)c4c(c(c(c(c4)O)C(=O)O)C)C3=O)O)O)O)O)CO

InChI

1S/C22H20O13/c1-4-8-5(2-6(24)9(4)22(33)34)13(25)10-11(15(8)27)16(28)12(18(30)17(10)29)21-20(32)19(31)14(26)7(3-23)35-21/h2,7,14,19-21,23-24,26,28-32H,3H2,1H3,(H,33,34)

InChI key

DGQLVPJVXFOQEV-UHFFFAOYSA-N

General description

Carmine is a red compound and is generally used with aluminum, iron and other metal salts to enhance its activity. During smear preparation, it is required for chromatin staining in fresh material. In presence of aluminum chloride, it is used for the staining of glycogen.

Application

Carmine has been used for the staining of mammary glands. It has been used for the staining of the chromosomes.


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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Hormone-sensing cells require Wip1 for paracrine stimulation in normal and premalignant mammary epithelium.
Tarulli GA, et al.
Breast Cancer Research, 15, R10-R10 (2013)
Dinesh K Ahirwar et al.
Oncogene, 37(32), 4428-4442 (2018-05-04)
The chemokine CXCL12 has been shown to regulate breast tumor growth, however, its mechanism in initiating distant metastasis is not well understood. Here, we generated a novel conditional allele of Cxcl12 in mice and used a fibroblast-specific Cre transgene along
Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice.
Williams TM, et al.
Molecular Biology of the Cell, 14, 1027-1027 (2003)