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Merck

H8125

L-Histidine monohydrochloride monohydrate

≥98% (HPLC)

Synonym(s):

L-α-Amino-β-(4-imidazolyl)propionic acid monohydrochloride

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About This Item

Empirical Formula (Hill Notation):
C6H9N3O2 · HCl · H2O
CAS Number:
5934-29-2
Molecular Weight:
209.63
NACRES:
NA.32
PubChem Substance ID:
57654272
eCl@ss:
32160406
UNSPSC Code:
12352209
MDL number:
MFCD00151027
Beilstein/REAXYS Number:
4168261
Assay:
≥98% (HPLC)
Quality level:
200

Key Documents

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InChI

1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1

SMILES string

O.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O

InChI key

CMXXUDSWGMGYLZ-XRIGFGBMSA-N

assay

≥98% (HPLC)

mp

254 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL, clear, colorless to very faintly yellow

Quality Level

200

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Application

L-Histidine monohydrochloride monohydrate has been used as a component of broth to match the tuna meat amino acid composition. It has also been used for partial rescue of the IMPL2 (myo-inositol monophosphatase) phenotype during seed development of Arabidopsis.

Biochem/physiol Actions

Histidine takes part in protein methylation. It is associated with the hemoglobin structure and function. Histidine is present in antioxidative dipeptides. It is involved in one-carbon unit metabolism.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000263741
0000263741
0000510956
0000510956
0000510954

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Modelling the effect of temperature, carbon dioxide, water activity and pH on growth and histamine formation by Morganella psychrotolerans
Emborg J and Dalgaard P
International Journal of Food Microbiology, 128(2), 226-233 (2008)
Yuko Sato et al.
Journal of plant research, 124(3), 385-394 (2010-10-21)
Myo-inositol monophosphatase (IMP) catalyzes the dephosphorylation of myo-inositol 3-phosphate in the last step of myo-inositol biosynthesis. IMP is also important in phosphate metabolism and is required for the biosynthesis of cell wall polysaccharides, phytic acid, and phosphatidylinositol. In Arabidopsis, IMP
Expression and functions of myo-inositol monophosphatase family genes in seed development of Arabidopsis
Sato Y, et al.
Journal of Plant Research, 124(3), 385-394 (2011)
A Bennett et al.
The Journal of nutrition, 129(12), 2236-2238 (1999-11-26)
Boron is required for the growth of vascular plants and embryonic development in fish. The molecular basis of boron's essentiality, however, remains unknown for both. The objective of this study was to determine whether yeast (Saccharomyces cerevisiae) could be used
Kiana Khadem-Abbassi et al.
Nanomaterials (Basel, Switzerland), 9(5) (2019-05-07)
This work describes the preparation of molecularly imprinted polymer (MIP)-modified core/shell CdTe0.5S0.5/ZnS quantum dots (QDs). The QDs@MIP particles were used for the selective and sensitive detection of dopamine (DA). Acrylamide, which is able to form hydrogen bonds with DA, and
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