X4002
Xanthine
≥99%, synthetic (organic), powder
Synonym(s):
2,6-Dihydroxypurine
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About This Item
Empirical Formula (Hill Notation):
C5H4N4O2
CAS Number:
Molecular Weight:
152.11
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
200-718-6
MDL number:
Beilstein/REAXYS Number:
8733
Assay:
≥99%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
1 M NaOH: 0.1 M, clear, colorless to light yellow
Product Name
Xanthine, BioUltra, ≥99%
biological source
synthetic (organic)
Quality Level
product line
BioUltra
assay
≥99%
form
powder
impurities
≤0.0005% Phosphorus (P), ≤0.1% Insoluble matter
ign. residue
≤0.1%
solubility
1 M NaOH: 0.1 M, clear, colorless to light yellow
anion traces
sulfate (SO42-): <0.05%
cation traces
Al: ≤0.0005%, Ca: ≤0.0005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.0005%, NH4+: ≤0.05%, Na: ≤0.005%, Pb: ≤0.001%, Zn: ≤0.0005%
SMILES string
O=C1NC(=O)c2nc[nH]c2N1
InChI
1S/C5H4N4O2/c10-4-2-3(7-1-6-2)8-5(11)9-4/h1H,(H3,6,7,8,9,10,11)
InChI key
LRFVTYWOQMYALW-UHFFFAOYSA-N
General description
Xanthine is a purine that can be produced in the purine metabolic pathway via different precursors:
- Guanine deamination by guanine deaminase
- Hypoxanthine conversion by xanthine oxidoreductase
Xanthine or its derivatives are naturally present in animal organs, yeast, potatoes, coffee beans, and tea.
Application
Xanthine has been used as a substrate for the determination of xanthine oxidase (XOD) inhibitory activity. It has also been used in the following systems:
- yeast culture
- human cell line culture
- recombinant viruses cloned as bacterial artificial chromosomes in Escherichia coli
Biochem/physiol Actions
Xanthine and xanthine oxidase are used to generate superoxide radicals to measure the activity of superoxide dismutase.
Features and Benefits
- Tested for trace metal content (fuller details in Properties section and on Specification Sheet)
- Tested for trace sulfate content (fuller details in Properties section and on Specification Sheet)
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Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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Related Content
Instructions
Insights from multispectral and molecular docking investigation on the xanthine oxidase inhibition by 1, 4-dicaffeoylquinic acid
Cao W, et al.
Journal of Molecular Structure, 1219, 128475-128475 null
Optimization of total phenolic contents, antioxidant, and in-vitro xanthine oxidase inhibitory activity of sunflower head
Mehmood A, et al.
CYTA-journal of Food, 16, 957-964 null
Resistance of postharvest biocontrol yeasts to oxidative stress: a possible new mechanism of action.
Raffaello Castoria et al.
Phytopathology, 93(5), 564-572 (2008-10-24)
ABSTRACT We detected the generation of the reactive oxygen species (ROS) superoxide anion ( O.(-) (2)) and hydrogen peroxide (H(2)O(2)) in apple wounds 2 immediately after wounding, and assessed the relationships between (i) timely colonization of apple wounds by biocontrol