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A propos de cet article
Formule empirique (notation de Hill) :
C10H14N2O5
Numéro CAS:
Poids moléculaire :
242.23
UNSPSC Code:
12352208
NACRES:
NA.51
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Solubility:
water: 10 mg/mL
Storage temp.:
10-30°C
Service technique
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RTECS - XP2071000
Merck USA index - 14, 9397
Quality Level
assay
≥98% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
white
solubility
water: 10 mg/mL
cation traces
heavy metals: ≤10 ppm
shipped in
ambient
storage temp.
10-30°C
SMILES string
[nH]1[c]([n](cc([c]1=O)C)C2OC(C(C2)O)CO)=O
InChI
1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)
InChI key
IQFYYKKMVGJFEH-UHFFFAOYSA-N
General description
Used in conjunction with hypoxanthine and aminopterin for the selection of hybridoma cell lines. Also reported to induce cell death in L-cells.
Preparation Note
Following reconstitution, sterilize by filtration using a 0.22 µm filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 year at -20°C.
Other Notes
Amenta, J.S., et al. 1993. In Vitro Cell Dev. Biol. Anim.29A, 855.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
Classe de stockage
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Contenu apparenté
Yaoyao Gu et al.
BMC cancer, 21(1), 784-784 (2021-07-09)
Minichromosome maintenance complex component 6 (MCM6), as an important replication permission factor, is involved in the pathogenesis of various tumors. Here we studied the expression of MCM6 in neuroblastoma and its influence on tumor characteristics and prognosis. Publicly available datasets
Evgeniia Prokhorova et al.
Molecular cell, 81(12), 2640-2655 (2021-05-22)
ARH3/ADPRHL2 and PARG are the primary enzymes reversing ADP-ribosylation in vertebrates, yet their functions in vivo remain unclear. ARH3 is the only hydrolase able to remove serine-linked mono(ADP-ribose) (MAR) but is much less efficient than PARG against poly(ADP-ribose) (PAR) chains in vitro.