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Merck

OP180

Anti-Noxa Mouse mAb (114C307)

liquid, clone 114C307, Calbiochem®

Synonyme(s) :

Anti-Noxa Antibody, Mouse Anti-Noxa, Noxa Detection Antibody

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A propos de cet article

NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
114C307, monoclonal
Species reactivity:
human
Application:
Citations:
76

Principaux documents

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Nom du produit

Anti-Noxa Mouse mAb (114C307), liquid, clone 114C307, Calbiochem®

biological source

mouse

antibody form

purified antibody

antibody product type

primary antibodies

clone

114C307, monoclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

human

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

dilution

(Immunoblotting (1-2 µg/mL, chemiluminescence))

isotype

IgG1

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... PMAIP1(5366)

Analysis Note

Negative Control
Normal mouse serum
Positive Control
RL-7 cell lysate

Application


Immunoblotting (1-2 g/ml, chemiluminescence)

Disclaimer

Toxicity: Standard Handling (A)

General description

Purified mouse monoclonal antibody. Recognizes the ~11 kDa Noxa protein.
Recognizes the ~11 kDa Noxa protein in RL-7 cells.
This Anti-Noxa Mouse mAb (114C307) is validated for use in Immunoblotting for the detection of Noxa.

Immunogen

Human
a recombinant protein consisting of human Noxa fused to GST

Other Notes

Antibody should be titrated for optimal results in individual system.
Oda, E., et al. 2000. Science288, 1053.

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In PBS, 0.05% BSA.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C;)

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Classe de stockage

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Nabanita Mukherjee et al.
Cancers, 12(8) (2020-08-09)
There is an urgent need to develop treatments for patients with melanoma who are refractory to or ineligible for immune checkpoint blockade, including patients who lack BRAF-V600E/K mutations. This is often the case in patients diagnosed with rare melanoma subtypes
Santi Rello-Varona et al.
Scientific reports, 9(1), 3816-3816 (2019-03-09)
Soft-tissue sarcomas (STS) are an uncommon and heterogeneous group of malignancies that result in high mortality. Metastatic STS have very bad prognosis due to the lack of effective treatments. Dinaciclib is a model drug for the family of CDK inhibitors.
Tao Hu et al.
Molecular carcinogenesis, 58(1), 42-54 (2018-09-06)
Increasing evidence suggests that deubiquitinase USP7 participates in tumor progression by various mechanisms and serves as a potential therapeutic target. However, its expression and role in esophageal cancer remains elusive; the anti-cancer effect by targeting USP7 still needs to be
Min Ji Seo et al.
Cell death & disease, 10(3), 187-187 (2019-02-24)
Gambogic acid (GA), a xanthonoid extracted from the resin of the tree, Garcinia hanburyi, was recently shown to exert anticancer activity in multiple studies, but the underlying action mechanism remains unclear. Here, we show that GA induces cancer cell death
Mateus Milani et al.
Cell death discovery, 5, 117-117 (2019-07-26)
Maintenance of mitochondrial integrity is critical for normal cellular homoeostasis. Most cells respond to stress stimuli and undergo apoptosis by perturbing mitochondrial structure and function to release proteins, such as cytochrome c, which are essential for the execution of the
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