D6518
Diethylenetriaminepentaacetic acid
≥99% (titration)
Synonyme(s) :
(Carboxymethylimino)bis(ethylenenitrilo)tetraacetic acid, N,N-Bis(2-[bis(carboxymethyl)amino]ethyl)glycine, DETAPAC, DTPA, Penta(carboxymethyl)diethylenetriamine, Pentetic acid
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A propos de cet article
Nom du produit
Diethylenetriaminepentaacetic acid, ≥99% (titration)
InChI key
QPCDCPDFJACHGM-UHFFFAOYSA-N
InChI
1S/C14H23N3O10/c18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27/h1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27)
SMILES string
OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CCN(CC(O)=O)CC(O)=O
biological source
synthetic (organic)
assay
≥99% (titration)
form
powder
mp
219-220 °C (lit.)
solubility
1 M HCl: 50 mg/mL, clear, colorless
storage temp.
room temp
Quality Level
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Application
- for cofilin activity assay
- to determine the specificity of superoxide in the transverse aortic constriction (TAC) hearts
- for Europium bead-based detection assays
- to detect reduced (S- active) or irreversibly oxidized (SO3H inactive) tyrosine-protein phosphatase non-receptor type 6 (SHP-1) in thymocytes
General description
Preparation Note
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Inhalation - Eye Irrit. 2 - Repr. 1B - STOT RE 2 Inhalation
target_organs
Respiratory Tract
Classe de stockage
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
flash_point_f
392.0 °F - closed cup
flash_point_c
200 °C - closed cup
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Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
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The lot specific COA document can be found by entering the lot number above under the "Documents" section.
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What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
How can I get Product D6518, Diethylenetriaminepentaacetic acid, to dissolve?
As is the case with other chelating agents such as EDTA and EGTA, the solubility of DTPA is a function of pH. Therefore, this compound can be solubilized with either the addition of acid such as a hydrochloric acid solution or (more likely) base such as a sodium hydroxide solution .
What are the pKa values for Product D6518, Diethylenetriaminepentaacetic acid?
The pKa values for the carboxyl groups as reported in the reference book "Data for Biochemical Research, 3rd ed., page 402, Oxford University Press, New York (1986)." are 1.8, 2.6, 4.4, 8.8, and 10.4.
What cations can be chelated with Product D6518, Diethylenetriaminepentaacetic acid (DTPA)?
DTPA forms stable complexes with most divalent and trivalent cations. Some examples are Fe3+, Cu2+, Ni2+, Pb2+, Zn2+, Fe2+, Mn2+, Ca2+, Mg2+, and Ba2+.
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