Diméthylsulfoxyde

Name: Diméthylsulfoxyde
Brand: SIGALD

puriss. p.a., dried, ≤0.02% water

Synonyme(s) :

DMSO, Sulfoxyde de méthyle

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About This Item

Formule linéaire :

(CH₃)₂SO

Numéro CAS:

67-68-5

Poids moléculaire :

78.13

UNSPSC Code:

12191502

NACRES:

NA.21

PubChem Substance ID:

329755094

EC Number:

200-664-3

Beilstein/REAXYS Number:

506008

MDL number:

MFCD00002089

assay:

≥99.9% (GC)

bp:

189 °C (lit.)

vapor pressure:

0.42 mmHg ( 20 °C)

Nom du produit

Diméthylsulfoxyde, puriss. p.a., dried, ≤0.02% water

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

SMILES string

CS(C)=O

vapor density

2.7 (vs air)

vapor pressure

0.42 mmHg ( 20 °C)

grade

puriss. p.a.

assay

≥99.9% (GC)

form

liquid

autoignition temp.

573 °F

quality

dried

expl. lim.

42 %, 63 °F

impurities

≤0.0001% heavy metals (as Pb)
≤0.001% free acid (as H₂SO₄)
≤0.002% non-volatile matter
≤0.02% water
≤0.03% water (Karl Fischer)

refractive index

n20/D 1.479 (lit.)

bp

189 °C (lit.)

mp

16-19 °C (lit.)

density

1.10 g/mL (lit.)

cation traces

Fe: ≤1 mg/kg

Quality Level

100

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Disclaimer

Refroidit facilement et revient doucement à la température de la pièce. Les produits solides peuvent être reliquéfiés par chauffage à la température ambiante sans abîmer le produit.

Application

Dimethyl sulfoxide (DMSO) has been used as a solvent in the high-throughput compound screening studies conducted on Mtb (Mycobacterium tuberculosis) H37Rv host cells.

General description

Dimethyl sulfoxide (DMSO) is a polar solvent. DMSO activated by various electrophiles (oxalyl chloride) has been used to oxidize various alcohols (primary, secondary, allylic, benzylic, hindered and bicyclic). Carbonyl compounds are formed as reaction products. It has been proposed as an alternate solvent for methyl cellosolve for use in ninhydrin reaction, due to its high stability.

Other Notes

For information on dimethyl sulfoxide miscibility, please visit the following link:
Dimethyl Sulfoxide Miscibility/Immiscibility Table

Classe de stockage

10 - Combustible liquids

wgk

WGK 1

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup

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Consulter la Bibliothèque de documents

A microscopic phenotypic assay for the quantification of intracellular mycobacteria adapted for high-throughput/high-content screening.

Christophe J Queval et al.

Journal of visualized experiments : JoVE, (83)(83), e51114-e51114 (2014-01-30)

Despite the availability of therapy and vaccine, tuberculosis (TB) remains one of the most deadly and widespread bacterial infections in the world. Since several decades, the sudden burst of multi- and extensively-drug resistant strains is a serious threat for the

Oxidation of alcohols by ?activated? dimethyl sulfoxide. A preparative, steric and mechanistic study.

Omura K and Swern D.

Tetrahedron, 34(11), 1651-1660 (1978)

Amino acid analysis: aqueous dimethyl sulfoxide as solvent for the ninhydrin reaction.

S Moore

The Journal of biological chemistry, 243(23), 6281-6283 (1968-12-10)

A RAPID PERMETHYLATION OF GLYCOLIPID, AND POLYSACCHARIDE CATALYZED BY METHYLSULFINYL CARBANION IN DIMETHYL SULFOXIDE.

S HAKOMORI

Journal of biochemistry, 55, 205-208 (1964-02-01)

Foretinib is effective therapy for metastatic sonic hedgehog medulloblastoma.

Claudia C Faria et al.

Cancer research, 75(1), 134-146 (2014-11-14)

Medulloblastoma is the most common malignant pediatric brain tumor, with metastases present at diagnosis conferring a poor prognosis. Mechanisms of dissemination are poorly understood and metastatic lesions are genetically divergent from the matched primary tumor. Effective and less toxic therapies

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