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93659

L-Tryptophane

Name: <SC>L</SC>-Tryptophane
Brand: SIGMA

≥99.5% (NT), BioUltra

Synonyme(s) :

Acide L-α-amino-3-indolepropionique, Acide (S)-2-amino-3-(3-indolyl)propionique

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A propos de cet article

Formule empirique (notation de Hill) :

C₁₁H₁₂N₂O₂

Numéro CAS:

73-22-3

Poids moléculaire :

204.23

NACRES:

NA.26

PubChem Substance ID:

57653570

eCl@ss:

32160406

UNSPSC Code:

12352209

EC Number:

200-795-6

MDL number:

MFCD00064340

Beilstein/REAXYS Number:

86197

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Propriétés

Nom du produit

L-Tryptophane, BioUltra, ≥99.5% (NT)

product line

BioUltra

Quality Segment

100

assay

≥99.5% (NT)

form

powder or crystals

optical activity

[α]20/D −31.5±1°, c = 1% in H₂O

impurities

insoluble matter, passes filter test

ign. residue

≤0.1%

loss

≤0.1% loss on drying, 20 °C (HV)

color

white

mp

280-285 °C (dec.) (lit.)

solubility

0.5 M HCl: 0.1 g/mL at 20 °C, clear, colorless to faintly yellow

anion traces

chloride (Cl^-): ≤50 mg/kg, sulfate (SO₄^2-): ≤50 mg/kg

cation traces

Al: ≤5 mg/kg, As: ≤0.1 mg/kg, Ba: ≤5 mg/kg, Bi: ≤5 mg/kg, Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤50 mg/kg, Li: ≤5 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Mo: ≤5 mg/kg, Na: ≤50 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Sr: ≤5 mg/kg, Zn: ≤5 mg/kg

absorption

cut-off at 326 nm in 0.5 M HCl at 0.5 M

application(s)

cell analysis

SMILES string

N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O

InChI

1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1

InChI key

QIVBCDIJIAJPQS-VIFPVBQESA-N

Description

Application

L-Tryptophan has been used as a nutritional supplement to study its effect on the circadian clock of primary cell lines. It has also been used as a test amino acid aerosol to study the variation in the fluorescence intensity of thermally-exposed bacterial bioaerosols.

Biochem/physiol Actions

Tryptophan (Trp) is one of the functional amino acids that are associated with growth, reproduction, maintenance and immunity. Increased Trp availability is necessary for the regulation of mood, cognition and behaviour. It is hypothesised that L-Trp might be useful in inducing sleep in healthy adults against the normal circadian rhythm. Trp uptake by the brain depends on the plasma ratio of Trp to all of the other LNAAs (large neutral amino acids). Higher the Trp:LNAAs ratio, greater is the Trp uptake.

Other Notes

Acide aminé précurseur de la sérotonine et de la mélatonine

In tryptophan-substituted Sephadex^® and Sepharose^™ for the improved chromatographic separation of cellulases; As spacer in isotachophoresis of serum proteins; Growth requirement of various microorganisms.

Legal Information

Sephadex is a registered trademark of Cytiva

Sepharose is a trademark of Cytiva

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Classe de stockage

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c