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Merck

D2438

Diméthylsulfoxyde

sterile-filtered, BioPerformance Certified, meets EP, USP testing specifications, suitable for hybridoma

Synonyme(s) :

DMSO, Sulfoxyde de méthyle

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About This Item

Formule linéaire :
(CH3)2SO
Numéro CAS:
67-68-5
Poids moléculaire :
78.13
UNSPSC Code:
12191502
NACRES:
NA.75
PubChem Substance ID:
24893688
EC Number:
200-664-3
Beilstein/REAXYS Number:
506008
MDL number:
MFCD00002089
grade:
BioPerformance Certified
technique(s):
cell culture | hybridoma: suitable
cryopreservation: suitable
bp:
189 °C (lit.)
vapor pressure:
0.42 mmHg ( 20 °C)

Nom du produit

Diméthylsulfoxyde, sterile-filtered, BioPerformance Certified, meets EP, USP testing specifications, suitable for hybridoma

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

SMILES string

CS(C)=O

grade

BioPerformance Certified

agency

USP XXIV
meets EP testing specifications
meets USP testing specifications

vapor density

2.7 (vs air)

vapor pressure

0.42 mmHg ( 20 °C)

sterility

sterile-filtered

form

liquid

autoignition temp.

573 °F

expl. lim.

42 %, 63 °F

technique(s)

cell culture | hybridoma: suitable
cryopreservation: suitable

impurities

≤0.1% water

color

colorless

refractive index

n20/D 1.479 (lit.)

bp

189 °C (lit.)

mp

16-19 °C (lit.)

solubility

H2O: miscible (completely)

density

1.10 g/mL (lit.)

Quality Level

400

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Catégories apparentées

Application

Le diméthylsulfoxyde a été utilisé comme véhicule témoin pour cultiver des cellules étoilées du foie (CEF) et induire leur activation in vivo. Il a également servi à préparer une solution-mère pour étudier la cytotoxicité de l'acide férulique sur des cellules de nucleus pulposus (NP).

Disclaimer

Refroidit facilement et revient doucement à la température de la pièce. Les produits solides peuvent être reliquéfiés par chauffage à la température ambiante sans abîmer le produit.

Features and Benefits

Produit stérilisé par filtration et prêt à l'emploi, commodément conditionné dans des flacons ambrés à septum et bouchon à vis. Conforme aux exigences d'analyse de l'USP et de la Ph. Eur.

General description

Le diméthylsulfoxyde (DMSO) est un solvant aprotique. Les molécules thérapeutiques et toxiques qui ne sont pas solubles dans l'eau sont souvent solubles dans le DMSO. L'association de l'azote liquide et d'un agent cryoprotecteur tel que le DMSO est couramment utilisée pour la conservation des cellules. Le DMSO permet de préparer des solutions mères de diverses molécules et sert également de témoin pour ces molécules. Il est utilisé dans les tests de migration cellulaire pour la dissolution des cellules post-migration. Le DMSO confirmé sans BPC par analyse répond également aux exigences des applications de biotechnologies et de génie tissulaire.

Classe de stockage

10 - Combustible liquids

wgk

WGK 1

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number
RNBM1118
RNBM0113
RNBM0642
RNBM0358
RNBL9232

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Si vous avez besoin d'une version particulière, vous pouvez rechercher un certificat spécifique par le numéro de lot.

Rechercher un(e) COA

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

  1. What is the molarity of DMSO?

    DMSO will have a molarity of 14.1M, based on a density of 1.1 g/mL and a molecular weight of 78.13 g/mol.

  2. What is the DMSO dissolved in?

    DMSO is not dissolved in any solvent. It is a pure chemical compound that is a liquid at room temperature.

  3. Where does DMSO come from?

    DMSO is known to have been isolated from tree bark in the past. It is now a commericially synthesized solvent.

  4. What concentration of DMSO do I use in a cell freezing media?

    DMSO is usually used at 1-10%, depending on the cell line.  For the cell freezing media that we offer, it is used at 8.7% concentration.

  5. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  6. What is the specification for 'pass' for cell freezing on the Certificate of Analysis for Dimethyl sulfoxide (DMSO)?

    Product D2438 is assessed for cell freezing.  Cells are frozen and stored at -70°C.  The cells are thawed, cultured and viability is assessed at 24 hours.  There is no evidence of cytotoxicity or abnormal cell growth.

  7. Dimethyl sulfoxide (DMSO) should be a liquid.  Why did it arrive as a solid?

    DMSO supercools easily, and re-melts slowly at room temperature. The melting point is 16-19 °C. The solidified product can be re-liquefied by warming to room temperature without detriment to the product.

  8. What is the basis for the endotoxin specification for Dimethyl sulfoxide (DMSO)?

    The industry standard for 'endotoxin free' is less than 1 EU/mL.

  9. What is the difference between Dimethyl sulfoxide (DMSO) Products. D1435 and D2438?

    Products D1435 and D2438 both meet the USP specifications. The D2438 is sterile-filtered, but D1435 is not. Furthermore, the D2438 is quality control tested for endotoxin and use-tested for cell freezing.

  10. What type of filter is used to sterile-filter Dimethyl sulfoxide (DMSO)?

    DMSO can be sterile-filtered through a 0.2 micron PTFE filter. The sterility testing is per the current US Pharmacopoeia method.

  11. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  12. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  13. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  14. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

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