M8574
D-(+)-Mannose
synthetic, ≥99% (GC)
Synonyme(s) :
D-Mannopyranose
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A propos de cet article
Formule empirique (notation de Hill) :
C6H12O6
Numéro CAS:
Poids moléculaire :
180.16
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
EC Number:
222-392-4
Beilstein/REAXYS Number:
1564373
MDL number:
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Laissez-nous vous aiderbiological source
synthetic
assay
≥99% (GC)
form
powder
optical activity
[α]25/D 13.5 to 14.9 °, c = 4% (w/v) in water
technique(s)
gas chromatography (GC): suitable
color
white to off-white
Quality Level
solubility
water: soluble 10 g/L at 20 °C
storage temp.
room temp
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Application
D-(+)-Mannose, a C-2 epimer of D-glucose, is used in the formation of glycan structure and glycosylation.
Biochem/physiol Actions
Mannose, a six-carbon carbohydrate, is the C-2 epimer of glucose and a critical sugar for protein glycosylation. Mannose can also be utilized by the brain as an alternative energy source.
Other Notes
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Classe de stockage
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Simone Torretta et al.
Nature communications, 11(1), 6343-6343 (2020-12-15)
D-mannose is a monosaccharide approximately a hundred times less abundant than glucose in human blood. Previous studies demonstrated that supraphysiological levels of D-mannose inhibit tumour growth and stimulate regulatory T cell differentiation. It is not known whether D-mannose metabolism affects
Brett Shannon et al.
Journal of immunology (Baltimore, Md. : 1950), 192(11), 5074-5082 (2014-04-25)
HSV-2 infection is common and generally asymptomatic, but it is associated with increased HIV susceptibility and disease progression. This may relate to herpes-mediated changes in genital and systemic immunology. Cervical cytobrushes and blood were collected from HIV-uninfected African/Caribbean women in
Charles D Murin et al.
Journal of virology, 88(17), 10177-10188 (2014-06-27)
The neutralizing anti-HIV-1 antibody 2G12 is of particular interest due to the sterilizing protection it provides from viral challenge in animal models. 2G12 is a unique, domain-exchanged antibody that binds exclusively to conserved N-linked glycans that form the high-mannose patch
Varnica Khetrapal et al.
Nucleic acids research, 43(13), e83-e83 (2015-03-25)
Creation of defined genetic mutations is a powerful method for dissecting mechanisms of bacterial disease; however, many genetic tools are only developed for laboratory strains. We have designed a modular and general negative selection strategy based on inducible toxins that
Cecilia W Huo et al.
Breast cancer research : BCR, 17, 79-79 (2015-06-05)
Mammographic density (MD), after adjustment for a women's age and body mass index, is a strong and independent risk factor for breast cancer (BC). Although the BC risk attributable to increased MD is significant in healthy women, the biological basis
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