Se connecter pour consulter les tarifs organisationnels et contractuels.
Sélectionner une taille de conditionnement
Changer de vue
A propos de cet article
UNSPSC Code:
12352203
NACRES:
NA.41
Conjugate:
unconjugated
Clone:
MHD4-46, monoclonal
Application:
FACS, FUNC
Citations:
-
Service technique
Besoin d'aide ? Notre équipe de scientifiques expérimentés est là pour vous.
Laissez-nous vous aiderconjugate
unconjugated
Quality Segment
antibody product type
primary antibodies
clone
MHD4-46, monoclonal
form
buffered aqueous solution
species reactivity
human
concentration
1 mg/ml
technique(s)
FUNC: suitable, flow cytometry: suitable
isotype
IgG1κ
UniProt accession no.
storage temp.
2-8°C
target post-translational modification
unmodified
Gene Information
human ... DLL4(54567)
General description
DLL4 (Delta-like 4) is one of five ligands of Notch receptors. It interacts with Notch1 and Notch4. DLL4 is up-regulated at sites of physiologic and pathologic angiogenesis, whereas its expression is low in most adult normal tissues. It is also highly expressed in human clear-cell renal carcinomas, bladder cancers, and breast cancers. Blocking the DLL4-Notch interaction seems to be a promissing therapeutic approach.
Immunogen
recombinant soluble human DLL4
Biochem/physiol Actions
The mouse monoclonal antibody MHD4-46 recognizes the extracellular domain of DLL4 (Delta-like ligand 4), a type I transmembrane protein which plays an important role in vascular development.
Physical form
Phosphate buffered saline (PBS), pH 7.4
Preparation Note
Purified by protein-A affinity chromatography.
Store at 2-8°C. Do not freeze.
Other Notes
The antibody solution should be gently mixed before use.
Still not finding the right product?
Essayez notre Outil de sélection de produits pour affiner vos choix.
Classe de stockage
12 - Non Combustible Liquids
wgk
WGK 1
Faites votre choix parmi les versions les plus récentes :
Déjà en possession de ce produit ?
Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.