SAB5701747
Anti-Phospho-PLC gamma 1 (PLCG1)-Y783 antibody produced in rabbit
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A propos de cet article
NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
mouse, rat, human
Application:
WB
Citations:
-
Service technique
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Laissez-nous vous aiderbiological source
rabbit
Quality Segment
antibody product type
primary antibodies
clone
polyclonal
form
liquid
species reactivity
mouse, rat, human
concentration
1.59 mg/mL
technique(s)
western blot: 1:500-1:2000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
phosphorylation (pTyr783)
Gene Information
human ... PLCG1(5335)
General description
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen
A phospho specific peptide corresponding to residues surrounding Y783 of human PLC gamma 1 (PLCG1)
Physical form
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
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Classe de stockage
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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