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Merck

115819

2,2′-Biphenol

99%

Synonym(s):

2,2′-Biphenyldiol, 2,2′-Dihydroxybiphenyl, 2,2′-Diphenol

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About This Item

Linear Formula:
HOC6H4C6H4OH
CAS Number:
Molecular Weight:
186.21
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
EC Number:
217-303-0
Beilstein/REAXYS Number:
1638363
MDL number:
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InChI key

IMHDGJOMLMDPJN-UHFFFAOYSA-N

InChI

1S/C12H10O2/c13-11-7-3-1-5-9(11)10-6-2-4-8-12(10)14/h1-8,13-14H

SMILES string

Oc1ccccc1-c2ccccc2O

assay

99%

form

solid

bp

315 °C (lit.)

mp

108-110 °C (lit.)

Quality Level

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

309.2 °F - closed cup - (External MSDS)

flash_point_c

154 °C - closed cup - (External MSDS)

ppe

dust mask type N95 (US), Eyeshields, Gloves


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V V Subrahmanyam et al.
Xenobiotica; the fate of foreign compounds in biological systems, 20(12), 1369-1378 (1990-12-01)
1. 14C-Phenol was metabolized by rat bone marrow homogenate and H2O2. The homogenate catalyst, however, was inactivated by preincubation with H2O2, presumably due to inactivation of the enzyme(s) involved in phenol metabolism. 2. The majority of the metabolized 14C-phenol was
Zwe-Ling Kong et al.
Bioorganic & medicinal chemistry letters, 15(1), 163-166 (2004-12-08)
The neolignans, magnolol 1 and honokiol 2 have been reported to inhibit the growth of several tumor cell lines in vitro and in vivo. The chemical structure of magnolol and honokiol consists of biphenyl skeleton with phenolic and allylic functionalities.
Atsushi Kuwahara et al.
The Journal of organic chemistry, 70(2), 413-419 (2005-01-18)
The double N-arylation of primary amines with 2,2'-biphenylylene ditriflates was investigated for the synthesis of multisubstituted carbazoles. Palladium complexes supported by 2-dicyclohexylphosphino-2'-methylbiphenyl or Xantphos [4,5-bis(diphenylphosphino)-9,9-dimethylxanthene] were found to be efficient catalysts for the reaction. The catalysts allow the use of
Christina DiMarco-Crook et al.
Journal of food science, 85(4), 1292-1301 (2020-03-08)
Chemoprevention strategies employing the use of multiple dietary bioactive components and their metabolites in combination offer advantages due to their low toxicity and potential synergistic interactions. Herein, for the first time, we studied the combination of curcumin and 3',4'-didemethylnobiletin (DDMN)
Sierra Rayne et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 4(11), 876-886 (2005-10-28)
Photochemical studies on a range of model dibenzo[1,4]dioxins were performed in aqueous and organic solutions. The compounds were found to undergo a photochemically initiated aryl-ether bond homolysis that yields reactive 2-spiro-6'-cyclohexa-2',4'-dien-1'-one and subsequent 2,2'-biphenylquinone intermediates. Under steady-state irradiation, the 2,2'-biphenylquinones

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