197777
2-(p-Chlorophenoxy)-2-methylpropionic acid
97%
Synonym(s):
α-(p-Chlorophenoxy)isobutyric acid, Clofibric acid
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About This Item
Linear Formula:
ClC6H4OC(CH3)2CO2H
CAS Number:
Molecular Weight:
214.65
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
212-925-9
MDL number:
Assay:
97%
Quality Level
assay
97%
mp
120-122 °C (lit.)
functional group
carboxylic acid, chloro
SMILES string
CC(C)(Oc1ccc(Cl)cc1)C(O)=O
InChI
1S/C10H11ClO3/c1-10(2,9(12)13)14-8-5-3-7(11)4-6-8/h3-6H,1-2H3,(H,12,13)
InChI key
TXCGAZHTZHNUAI-UHFFFAOYSA-N
Gene Information
human ... PPARA(5465), PPARG(5468)
mouse ... Ppara(19013), Pparg(19016)
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R Salgado et al.
Journal of hazardous materials, 241-242, 182-189 (2012-10-16)
Clofibric acid (CLF) is the pharmaceutically active metabolite of lipid regulators clofibrate, etofibrate and etofyllinclofibrate, and it is considered both environmentally persistent and refractory. This work studied the biotransformation of CLF in aerobic sequencing batch reactors (SBRs) with mixed microbial
K Sumida et al.
Chemosphere, 33(11), 2201-2207 (1996-12-01)
Peroxisome proliferators are generally known as activators of fatty acid beta-oxidation which is one of degradation pathways. However, since it is unknown whether peroxisome proliferators have an effect on biosynthesis of fatty acid or not, we commenced to study if
Dong Qing Zhang et al.
Environmental pollution (Barking, Essex : 1987), 167, 124-131 (2012-05-09)
This study evaluated the effect of continuous and batch feeding on the removal of 8 pharmaceuticals (carbamazepine, naproxen, diclofenac, ibuprofen, caffeine, salicylic acid, ketoprofen and clofibric acid) from synthetic wastewater in mesocosm-scale constructed wetlands (CWs). Both loading modes were operated