5.06129
α-(Methylamino)isobutyric Acid
Synonym(s):
α-(Methylamino)isobutyric Acid, Neutral Amino Acid Transporter A inhibitor, MeBIA
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About This Item
Empirical Formula (Hill Notation):
C5H11NO2
CAS Number:
Molecular Weight:
117.15
UNSPSC Code:
12352106
NACRES:
NA.77
MDL number:
Assay:
≥98% (TLC)
Form:
solid
Storage condition:
OK to freeze, protect from light
assay
≥98% (TLC)
Quality Segment
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
white
solubility
water: 100 mM
storage temp.
−20°C
SMILES string
[N+H2](C(C)(C)C(=O)[O-])C
InChI
1S/C5H11NO2/c1-5(2,6-3)4(7)8/h6H,1-3H3,(H,7,8)
InChI key
DLAMVQGYEVKIRE-UHFFFAOYSA-N
General description
A glutamine transport inhibitor selective for Na+-dependent amino acid transport system A. Used in studying the functional roles of neurotransmissions mediated by amino acids.
Biochem/physiol Actions
Primary Target
Glutamine transporter
Glutamine transporter
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Young, H., et al., 2013. Am. J. Physiology-Cell Physiology.298, C1401.
Lee, Y., et al., 2013. J. Psych. & Neurosci.: JPN.38, 183.
Blot, A., et al. 2009. Neurosci.164, 998.
Lee, Y., et al., 2013. J. Psych. & Neurosci.: JPN.38, 183.
Blot, A., et al. 2009. Neurosci.164, 998.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
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Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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