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29210

Eucalyptol

analytical standard

Synonym(s):

1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octane, 1,8-Cineole, 1,8-Epoxy-p-menthane

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About This Item

Empirical Formula (Hill Notation):
C10H18O
CAS Number:
470-82-6
Molecular Weight:
154.25
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
329753321
EC Number:
207-431-5
Beilstein/REAXYS Number:
105109
MDL number:
MFCD00167977
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grade

analytical standard

Quality Level

100

assay

≥99.0% (GC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

refractive index

n20/D 1.457 (lit.), n20/D 1.458

bp

176-177 °C (lit.)

mp

1-2 °C (lit.)

density

0.921 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

format

neat

storage temp.

2-8°C

SMILES string

C[C@]12CC[C@H](CC1)C(C)(C)O2

InChI

1S/C10H18O/c1-9(2)8-4-6-10(3,11-9)7-5-8/h8H,4-7H2,1-3H3/t8-,10+

InChI key

WEEGYLXZBRQIMU-WAAGHKOSSA-N

General description

Eucalyptol is a saturated monoterpene. It is a volatile oil with medicinal values naturally found in eucalyptus oil. It is a isoprenoid with 2-isoprene subunits (C10).

Application

Eucalyptol may be used as a reference standard for the determination of the analyte in:
  • Melon fruits by headspace solid-phase microextraction (HS-SPME) and gas chromatography-mass spectrometry.
  • Chrysanthemum flower by pressurized hot water extraction (PHWE) followed by headspace solid-phase microextraction (HS-SPME) and gas chromatography-mass spectrometry.
  • Pharmaceutical formulations by full evaporation technique extraction followed by capillary gas chromatography and ion-trap detection.
  • External analgesic pharmaceutical formulations by densitometric HPTLC analysis.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
It has been used as reference standard in densitometric HPTLC analysis for the determination of Eucalyptol from external analgesic pharmaceutical formulations.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This compound is commonly found in plants of the genus: achillea angelica cinnamomum curcuma eucalyptus mentha salvia thymus valeriana zingiber

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pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Warning

hcodes

H226,H317

Hazard Classifications

Flam. Liq. 3 - Skin Sens. 1

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

125.6 °F - closed cup

flash_point_c

52 °C - closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP3743
BCCL2728
BCCM0987
BCCH2463
BCCF6903

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Volatile organic compounds determined in pharmaceutical products by full evaporation technique and capillary gas chromatography/ion-trap detection.
Schuberth, Jan
Analytical Chemistry, 68(8), 1317-1320 (1996)
Fast quantitative determination of aroma volatile constituents in melon fruits by headspace--solid-phase microextraction and gas chromatography-mass spectrometry.
Verzera A, et al.
Food Analytical Methods, 4(2), 141-149 (2011)
Anti-inflammatory activity of 1.8-cineol (eucalyptol) in bronchial asthma: a double-blind placebo-controlled trial.
Juergens, U. R., et al.
Respiratory Medicine, 97.3, 250-256 (2003)
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