33347
AOZ
VETRANAL®, analytical standard
Synonym(s):
3-Amino-2-oxazolidinone, NSC 111187, NSC 196570, NSC 38250
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About This Item
Empirical Formula (Hill Notation):
C3H6N2O2
CAS Number:
Molecular Weight:
102.09
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
201-299-2
Beilstein/REAXYS Number:
109430
MDL number:
InChI key
KYCJNIUHWNJNCT-UHFFFAOYSA-N
InChI
1S/C3H6N2O2/c4-5-1-2-7-3(5)6/h1-2,4H2
SMILES string
NN1CCOC1=O
grade
analytical standard
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
mp
63-69 °C
suitability
passes test for identity
application(s)
clinical testing
format
neat
Quality Level
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Application
The analytical standard can be used as follows:
- Development of an electrochemical impedimetric immunosensor based on immobilization of a monoclonal antibody on a gold electrode, to determine AOZ in six food samples
- Multi-residue analysis of four nitrofuran metabolites residues in 120 fish samples by ultra high-performance liquid chromatography (UHPLC) combined with tandem mass spectrometry
- Detection and measurement of AOZ in tissue samples obtained from four animals by immunochromatography test stripes based on colloidal gold-monoclonal antibody
- LC-MS/MS analysis of nitrofuran and nitroimidazole metabolite residues in honey samples after their extraction by a modified QuEChERS-based method
- Screening of nitrofuran metabolite residues from shrimp muscle samples by an HPLC method combined with diode array detection
General description
AOZ, also known as 3-amino-2-oxazolidinone, is a metabolite of the synthetic nitrofuran veterinary antibiotic ― furazolidone.
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Quan Wang et al.
Analytical and bioanalytical chemistry, 410(1), 223-233 (2017-11-01)
There is an urgent need for the rapid and simultaneous detection of multiple analytes present in a sample matrix. Here, a multiplex immunochromatographic test (multi-ICT) was developed that successfully allowed for the rapid and simultaneous detection of four major nitrofuran
Monoclonal antibody-based ELISA for the quantification of nitrofuran metabolite 3-amino-2-oxazolidinone in tissues using a simplified sample preparation
Diblikova I, et al.
Analytica Chimica Acta, 540, 285-292 (2005)
Pierre Guichard et al.
Food chemistry, 342, 128389-128389 (2020-12-04)
LC-MS/MS method for confirmation of nitrofuran metabolites in meat and aquaculture products, including the nifursol metabolite (DNSH), was developed. The nitrofuran metabolites investigated were as follows: 3-amino-2-oxazolidinone (AOZ), 3-amino-5-morpholinomethyl-2-oxazolidinone (AMOZ), 1-aminohydantoine (AHD), semicarbazide (SEM) and 3,5-dinitrosalicylic acid hydrazide (DNSH). The
Kangkang Wang et al.
ACS omega, 5(30), 18887-18893 (2020-08-11)
Nitrofuran (NF) is a class of broad-spectrum antibiotics that are used illegally in animal feeding. NF and its metabolites have proven to pose potential risk to human health. To address the current analytical needs to quantify low levels of NF
Jinyan Gong et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1146, 122018-122018 (2020-04-26)
This study established a validated analytical method for the first time on the determination of nitrofuran metabolites, including semicarbazide (SEM), 1-aminohydantoin (AHD), 3-amino-2-oxazolidinone (AOZ) and 3-amino-5-morpholinomethyl-2-oxazolinone (AMOZ) in gelatin Chinese medicine. A C18 column with the mobile phase consisting of
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