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Merck

P6863

PDAM

≥70% purity (HPLC), for HPLC derivatization, solid

Synonym(s):

1-Pyrenyldiazomethane, Pyrene, 1-(diazomethyl)

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About This Item

Empirical Formula (Hill Notation):
C17H10N2
CAS Number:
Molecular Weight:
242.27
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
MA.02
MDL number:
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Product Name

PDAM, derivatization grade (HPLC)

grade

derivatization grade (HPLC)

Quality Level

assay

≥70% (HPLC)

form

solid

technique(s)

titration: suitable

λmax

338-344 nm

fluorescence

λem 371-379 nm

application(s)

diagnostic assay manufacturing
hematology
histology

shipped in

dry ice

storage temp.

−20°C

SMILES string

[N-]=[N+]=Cc1ccc2ccc3cccc4ccc1c2c34

InChI

1S/C17H10N2/c18-19-10-14-7-6-13-5-4-11-2-1-3-12-8-9-15(14)17(13)16(11)12/h1-10H

InChI key

PEIBAWRLFPGPAT-UHFFFAOYSA-N

Application

Fluorescent diazoalkane useful as an HPLC derivatization reagent for carboxylic acid detection with better detection limit parameters and greater chemical stability than the commonly used 9-anthryldiazomethane.

Other Notes

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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G A Mills et al.
Journal of chromatography. B, Biomedical sciences and applications, 730(1), 113-122 (1999-08-07)
Short chain fatty acids (SFCAs) are nutritionally important products of colonic bacteria. Their analysis in faeces is problematic. We report a headspace solid-phase microextraction procedure in which faecal SCFAs are derivatised on the fibre in-situ with 1-pyrenyldiazomethane. With this method
O L Brekke et al.
Journal of lipid research, 38(9), 1913-1922 (1997-11-05)
A highly sensitive method to determine agonist-induced release of endogenous fatty acids from cells in culture was developed using high-performance liquid chromatography and fluorescence detection. Fatty acids were selectively derivatized with 1-pyrenyldiazomethane and separated on a LC18 reversed phase column
F Iohan et al.
Journal of chromatography, 564(1), 27-41 (1991-03-08)
A new procedure is described for the detection of the acidic metabolites of cortisol (cortoic acids) as the pyrenylmethyl-21-oic esters. The derivatizing reagent, diazomethylpyrene, was prepared by an improved procedure. The reagent was used at room temperature, required no catalyst
Carlos García et al.
Biological research, 36(2), 171-183 (2003-09-30)
Diarrhetic shellfish poisoning (DSP) is a gastrointestinal disease caused by lipid soluble polyether toxins produced by dinoflagellates and accumulated in shellfish. Diarrhetic shellfish poisoning is a worldwide threat to public health and the shellfish industry. To date, only four lipid
Liquid chromatographic determination of biotin by using 1-pyrenyldiazomethane as a pre-column fluorescent labelling reagent.
T Yoshida et al.
Journal of chromatography, 456(2), 421-426 (1988-12-16)

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