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About This Item
Empirical Formula (Hill Notation):
C30H49Br2N3
CAS Number:
Molecular Weight:
611.54
UNSPSC Code:
12171500
PubChem Substance ID:
NACRES:
NA.47
MDL number:
Product Name
SynaptoGreen™ C4, ≥95% (HPLC), solid
Quality Level
assay
≥95% (HPLC)
form
solid
color
dark red
solubility
DMSO: soluble, H2O: soluble
εmax
≥50000 at 507-513 nm in methanol
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
−20°C
SMILES string
[Br-].[Br-].CCCCN(CCCC)c1ccc(\C=C\c2cc[n+](CCC[N+](CC)(CC)CC)cc2)cc1
InChI
1S/C30H49N3.2BrH/c1-6-11-23-32(24-12-7-2)30-18-16-28(17-19-30)14-15-29-20-25-31(26-21-29)22-13-27-33(8-3,9-4)10-5;;/h14-21,25-26H,6-13,22-24,27H2,1-5H3;2*1H/q+2;;/p-2
InChI key
VZUVCAGXYLMFEC-UHFFFAOYSA-L
General description
SynaptoGreen™ C4 is an oxonol dye that helps in the rapid detection of an antibiotic′s effect on bacterial viability. It is a fluorescent dye that is used in optical imaging studies to determine synaptic activity by staining synaptic vesicles at the nerve terminal or the neuromuscular junction. It is equivalent to FM1-43.
Application
SynaptoGreen™ C4 has been used to label cultured neurons grown on EM grids for fluorescent labeling, live light microscopy and imaging studies.
Biochem/physiol Actions
A fluorescent nerve terminal dye suitable for monitoring synaptic activity at synapses and at neuromuscular junctions.
Other Notes
Component of NTSI, also sold individually.
Legal Information
SynaptoGreen is a trademark of Biotium, Inc.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Christopher R Heier et al.
EMBO molecular medicine, 5(10), 1569-1585 (2013-09-10)
Absence of dystrophin makes skeletal muscle more susceptible to injury, resulting in breaches of the plasma membrane and chronic inflammation in Duchenne muscular dystrophy (DMD). Current management by glucocorticoids has unclear molecular benefits and harsh side effects. It is uncertain
Journal of Immunology, 179(2) null
Yalda Moayedi et al.
Scientific reports, 8(1), 9975-9975 (2018-07-04)
Oral mechanoreception is implicated in fundamental functions including speech, food intake and swallowing; yet, the neuroanatomical substrates that encode mechanical stimuli are not well understood. Tactile perception is initiated by intricate mechanosensitive machinery involving dedicated cells and neurons. This signal