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Merck

Y0001487

Butyl methacrylate

European Pharmacopoeia (EP) Reference Standard

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About This Item

Linear Formula:
CH2=C(CH3)COO(CH2)3CH3
CAS Number:
Molecular Weight:
142.20
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
202-615-1
Beilstein/REAXYS Number:
773960
MDL number:
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grade

pharmaceutical primary standard

vapor density

4.91 (15 °C, vs air)

vapor pressure

2 mmHg ( 20 °C)

API family

butylated methacrylate copolymer

autoignition temp.

562 °F

expl. lim.

2-8 %

manufacturer/tradename

EDQM

refractive index

n20/D 1.423 (lit.)

bp

162-165 °C (lit.)

density

0.894 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

CCCCOC(=O)C(C)=C

InChI

1S/C8H14O2/c1-4-5-6-10-8(9)7(2)3/h2,4-6H2,1,3H3

InChI key

SOGAXMICEFXMKE-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Butyl methacrylate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.


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pictograms

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signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

119.3 °F - closed cup

flash_point_c

48.5 °C - closed cup



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Íris Duarte et al.
Pharmaceutical research, 32(1), 222-237 (2014-08-20)
To present a new screening methodology intended to be used in the early development of spray-dried amorphous solid dispersions. A model that combines thermodynamic, kinetic and manufacturing considerations was implemented to obtain estimates of the miscibility and phase behavior of
Makoto Ishida et al.
Drug development and industrial pharmacy, 40(8), 1054-1064 (2013-06-21)
Abstract The applicability of porous spherical silica (PSS) was evaluated as core particles for pharmaceutical products by comparing it with commercial core particles such as mannitol (NP-108), sucrose and microcrystalline cellulose spheres. We investigated the physical properties of core particles
Kateřina Punčochová et al.
International journal of pharmaceutics, 469(1), 159-167 (2014-04-23)
The objective of this study was to investigate the effect of different polymeric carriers in solid dispersions with an active pharmaceutical ingredient (API) on their water vapour sorption equilibria and the influence of the API-polymer interactions on the dissolution rate