C2404
Citric acid
anhydrous, suitable for cell culture, suitable for plant cell culture
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About This Item
Linear Formula:
HOC(COOH)(CH2COOH)2
CAS Number:
Molecular Weight:
192.12
NACRES:
NA.25
PubChem Substance ID:
eCl@ss:
39021801
UNSPSC Code:
12161700
EC Number:
201-069-1
MDL number:
Beilstein/REAXYS Number:
782061
Assay:
≥97% (GC)
Form:
powder
Quality Level
assay
≥97% (GC)
form
powder
expl. lim.
8 %, 65 °F
technique(s)
cell culture | mammalian: suitable, cell culture | plant: suitable
pH
1.8 (25 °C, 50 g/L)
pKa
(1) 3.13, (2) 4.76, (3) 6.4
mp
153-159 °C (lit.)
solubility
water: 50 mg/mL, clear to very slightly hazy, colorless
density
1.67 g/cm3 at 20 °C
SMILES string
OC(=O)CC(O)(CC(O)=O)C(O)=O
InChI
1S/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
InChI key
KRKNYBCHXYNGOX-UHFFFAOYSA-N
Gene Information
human ... SRC(6714)
Application
In addition to its function as an iron chelator, citrate can support cholesterol/sterol, ubiquinone and isoprenoid biosynthesis in cell culture applications.
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Konrad Hoetzenecker et al.
European heart journal, 36(11), 676-685 (2013-01-17)
Supernatants of serum-free cultured mononuclear cells (MNC) contain a mix of immunomodulating factors (secretome), which have been shown to attenuate detrimental inflammatory responses following myocardial ischaemia. Inflammatory dilated cardiomyopathy (iDCM) is a common cause of heart failure in young patients.
Wayne B Batchelor et al.
Circulation, 106(12), 1470-1476 (2002-09-18)
The relative anti-aggregatory effects of currently prescribed platelet glycoprotein IIb/IIIa receptor antagonists during and after percutaneous coronary intervention for acute coronary syndromes have not been established. We randomized 70 acute coronary syndrome patients undergoing percutaneous coronary intervention to receive abciximab
Tetsuji Sawada et al.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 18(1), 119-128 (2014-02-04)
The G-Project committee was erected by the Japan Society for Gastroenterological Carcinogenesis with an aim of establishing a new classification scheme based on molecular biological characteristics that would supplement the conventional TNM classification to better predict outcome. In a literature