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About This Item
Biological source:
bovine plasma
Form:
solution
Technique(s):
cell culture | mammalian: suitable
Product Name
Fibronectin bovine plasma, solution, sterile-filtered, BioReagent, suitable for cell culture
biological source
bovine plasma
Quality Level
sterility
sterile-filtered
product line
BioReagent
form
solution
packaging
pkg of 1 mg, pkg of 2 mg, pkg of 5 mg
technique(s)
cell culture | mammalian: suitable
surface coverage
1‑5 μg/cm2
UniProt accession no.
binding specificity
Peptide Source: Collagen
, Peptide Source: Fibrinogen
shipped in
wet ice
storage temp.
2-8°C
Gene Information
bovine ... FN1(280794)
General description
Fibronectin is a ubiquitous protein of the extracellular matrix. It is a mosaic protein, that is made up of three types of repeating modular consensus amino acid sequences. Fibronectins belongs to a class of high-molecular-weight glycoproteins. Cellular fibronectin is expressed by fibroblasts and plasma fibronectin is usually liberated by hepatocytes.
Application
Fibronectin (FN) bovine plasma has been used in:
- fibronectin and adsorption analysis (ELISA (enzyme-linked immunosorbent assay))
- transwell migration
- fibronectin assay
Biochem/physiol Actions
Fibronectins participate in cell adhesion, cytoskeletal organization, oncogenic transformation, cell migration, phagocytosis, hemostasis, and embryonic differentiation.
Analysis Note
Protein homogeneity is evaluated by immunoelectrophoresis.
Other Notes
Product F1141, Fibronectin from bovine plasma is a solution in 0.05 M TBS pH 7.5.
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signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
Storage Class
12 - Non Combustible Liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
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CCL2/CCR2 chemokine signaling coordinates survival and motility of breast cancer cells through Smad3 and p42/44MAPK dependent mechanisms
Fang W B, et al.
The Journal of biological chemistry, jbc-M112 (2012)
Enhanced fibronectin adsorption on carbon nanotube/poly (carbonate) urethane: independent role of surface nano-roughness and associated surface energy
Khang D, et al.
Biomaterials, 28(32), 4756-4768 (2007)
FIBRONECTIN AUTOANTIBODIES
Autoantibodies, 221-251 (2007)
