L5751
L-Lysine dihydrochloride
≥98% (HPLC), suitable for ligand binding assays
Synonym(s):
(S)-2,6-Diaminohexanoic acid dihydrochloride
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About This Item
Linear Formula:
NH2(CH2)4CH(NH2)COOH · 2HCl
CAS Number:
Molecular Weight:
219.11
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
211-518-3
MDL number:
Beilstein/REAXYS Number:
4539715
Product Name
L-Lysine dihydrochloride, ≥98% (HPLC)
Quality Level
assay
≥98% (HPLC)
form
powder
technique(s)
ligand binding assay: suitable
color
white to faint yellow
mp
200-206 °C (lit.)
SMILES string
Cl[H].Cl[H].NCCCC[C@H](N)C(O)=O
InChI
1S/C6H14N2O2.2ClH/c7-4-2-1-3-5(8)6(9)10;;/h5H,1-4,7-8H2,(H,9,10);2*1H/t5-;;/m0../s1
InChI key
JBBURJFZIMRPCZ-XRIGFGBMSA-N
Biochem/physiol Actions
L-Lysine is an essential proteinogenic α amino acid used in a wide range of applications including as a supplement in cell culture media; a substrate of enzymes such as L-lysine oxidase (EC 1.4.3.14); a component of poly-lysine polymers; and a substrate for oxidation and glycation mechanism studies.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Liying Yao et al.
PloS one, 11(2), e0149948-e0149948 (2016-02-24)
Myeloid-derived suppressor cells (MDSCs) are potent suppressors of T cell immunity in tumors and inflammatory diseases. They are identified by surface expression of CD11b+Gr1+ in mice, and CD11b+Gr1+ cells accumulate in the livers of obese mice. However, many myeloid cells
Zachery R Jarrell et al.
Aging, 12(13), 13555-13570 (2020-06-20)
Acylcarnitines transport fatty acids into mitochondria and are essential for β-oxidation and energy metabolism. Decreased mitochondrial activity results in increased plasma acylcarnitines, and increased acylcarnitines activate proinflammatory signaling and associate with age-related disease. Changes in acylcarnitines associated with healthy aging
Gong Zhang et al.
Journal of agricultural and food chemistry, 59(22), 12037-12046 (2011-10-11)
A sensitive and reliable LC-(ESI)MS/MS method was developed and validated for the simultaneous analysis of five common advanced glycation endproducts (AGEs) after enzymatic digestion in raw and roasted almonds. AGEs included carboxymethyl-lysine (CML), carboxyethyl-lysine (CEL), pyralline (Pyr), argpyrimidine (Arg-p), and