317802
4-(4-Isothiocyanatophenylazo)-N,N-dimethylaniline
97%
Synonym(s):
4-(Dimethylamino)azobenzene-4′-isothiocyanate, DABITC
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About This Item
Linear Formula:
SCNC6H4N=NC6H4N(CH3)2
CAS Number:
Molecular Weight:
282.36
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
231-521-3
Beilstein/REAXYS Number:
752568
MDL number:
InChI key
OSWZKAVBSQAVFI-ISLYRVAYSA-N
InChI
1S/C15H14N4S/c1-19(2)15-9-7-14(8-10-15)18-17-13-5-3-12(4-6-13)16-11-20/h3-10H,1-2H3/b18-17+
SMILES string
CN(C)c1ccc(cc1)\N=N\c2ccc(cc2)N=C=S
assay
97%
form
crystals
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
Related Categories
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1 - Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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J Hempel et al.
FEBS letters, 194(2), 333-337 (1986-01-06)
A synthetic peptide analog, with one peptide carbonyl group replaced by a methylene bridge, was submitted to structural analysis by Edman degradation. Multiple cleavages were obtained in the first cycle, due to phenylthiocarbamylation of the internal secondary amine as well
E Kinoshita et al.
Bioscience, biotechnology, and biochemistry, 62(8), 1488-1491 (1998-10-03)
An easy and highly sensitive method for measuring histamine by HPLC analysis coupled with precolumn derivatization was established. The amino group of histamine was completely colorimetrically labelled with 4-N,N-dimethylamino-azobenzene-4'-isothiocyanate (DABITC) in the presence of sodium bicarbonate at 90 degrees C
Evidence for the formation of a novel glutathione conjugate in the metabolism of an aromatic amine derivative.
D H Hutson et al.
Drug metabolism and disposition: the biological fate of chemicals, 12(4), 523-524 (1984-07-01)
P P Nair et al.
Steroids, 59(3), 212-216 (1994-03-01)
N-epsilon-lithocholyl lysine (NELL) is a component of tissue-bound lithocholic acid (TBL). The isolation of NELL from native protein sources was simulated by hydrolysis of lithocholyl-bovine serum albumin (BSA) (synthesized by coupling lithocholyl-N-hydroxysuccinimide to fatty acid-free BSA) by digestion with a
P M Fischer et al.
Analytical biochemistry, 177(1), 46-49 (1989-02-15)
A single-column high-performance liquid chromatographic separation of 4-N,N-dimethylaminoazobenzene 4'-thiohydantoin amino acid derivatives, generated during polypeptide sequence analysis by the 4-N,N-dimethylaminoazobenzene 4'-isothiocyanate/phenylisothiocyanate double coupling technique, is described. Recovery of the serine and threonine derivatives was improved by substituting boron trifluoride-diethyl etherate
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