I1887
Indapamide
analytical standard, for drug analysis
Synonym(s):
N-(4-Chloro-3-sulfamoylbenzamido)-2-methylindoline
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About This Item
Empirical Formula (Hill Notation):
C16H16ClN3O3S
CAS Number:
Molecular Weight:
365.83
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
248-012-7
MDL number:
Quality Level
technique(s)
gas chromatography (GC): suitable, HPLC: suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
SMILES string
CC1Cc2ccccc2N1NC(=O)c3ccc(Cl)c(c3)S(N)(=O)=O
InChI
1S/C16H16ClN3O3S/c1-10-8-11-4-2-3-5-14(11)20(10)19-16(21)12-6-7-13(17)15(9-12)24(18,22)23/h2-7,9-10H,8H2,1H3,(H,19,21)(H2,18,22,23)
InChI key
NDDAHWYSQHTHNT-UHFFFAOYSA-N
Gene Information
human ... SLC12A3(6559)
General description
Indapamide is a deuretic drug, belonging to the class of benzothiadiazines. It is commonly used for the treatment of hypertension. The drug acts by causing a drop in systolic, diastolic and mean blood pressure.
Application
Indapamide may be used as an internal standard for the quantification of the analyte in pharmaceutical formulations and biological samples using different analytical techniques
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
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signalword
Warning
hcodes
Hazard Classifications
Lact. - Repr. 2
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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Simultaneous estimation of amlodipine besylate and indapamide in a pharmaceutical formulation by a high performance liquid chromatographic (RP-HPLC) method
Patel.BD, et al.
Scientia Pharmaceutica, 80(3), 581-590 (2012)
Alina Porfire et al.
Journal of pharmaceutical and biomedical analysis, 70, 301-309 (2012-08-14)
This paper describes the development and application of NIR-chemometric methods for active content assay and pharmaceutical characterization (granulometric analysis and flowability assessment) of indapamide powder blends for tabletting. Indapamide powder blends were prepared and their NIR spectra were recorded in
A selective HPLC method for the determination of indapamide in human whole blood: Application to a bioequivalence study in Chinese volunteers
Hang J-T, et al.
Journal of Pharmaceutical and Biomedical Analysis, 40(1), 202-205 (2006)