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About This Item
Empirical Formula (Hill Notation):
C25H31BF2N2O2S
CAS Number:
Molecular Weight:
472.40
NACRES:
NA.21
Assay:
≥98% (HPLC)
Form:
(Powder, film, or oil)
Storage condition:
desiccated
Quality Segment
assay
≥98% (HPLC)
form
(Powder, film, or oil)
storage condition
desiccated
color
red to black
storage temp.
-10 to -25°C
SMILES string
F[B-]1([N+]2=C(C3=CC=CS3)C=CC2=CC4=CC=C(CCCCCCCCCCCC(O)=O)N14)F
General description
BODIPY 558/568 C12, also known as BODIPY-red C12, is an orange-red fluorescent saturated fatty acid analog structurally resembling an 18-carbon fatty acid.
Application
BODIPY 558/568 C12, Red is suitable for use in:
- investigating lipid dynamics, such as the formation, growth, and breakdown of lipid droplets
- fluorescence microscopy techniques
- cell labeling following molecules throughout cellular processes
- studying protein–protein interactions
Biochem/physiol Actions
BODIPY 558/568 C12 monitors lipid flux/fatty acid trafficking in live cells and fixed cells. In cells, red-C12 probe primarily localizes in neutral lipids within lipid droplets (LDs) and to the endoplasmic reticulum (ER), tracing lipid accumulation in these structures as well as in mitochondria and peroxisomes. BDP 558/568 C12 reveals fatty acid transfer from lipid droplet triacylglycerides (TAGs) to mitochondria and demonstrates how these fatty acids are esterified and stored in lipid droplets within the cytotrophoblast layer. Red C12 features a sharp fluorescence peak and high quantum yield, maintaining stable fluorescence across various physiological conditions and resisting changes in environmental polarity and pH. Excites at ~558 nm and emits at ~568 nm. BODIPY = boron dipyrromethene.
Disclaimer
Hygroscopic Store with dessicant
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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