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852044 FMOC-Asn(Trt)-OH

FMOC-Asn(Trt)-OH N-α-Fmoc-N-ß-trityl-L-asparagine Novabiochem®. CAS 132388-59-1, molar mass 596.69 g/mol.

FMOC-Asn(Trt)-OH MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 132388-59-1 Molar Mass: 596.69 g/mol Hill Formula: C₃₈H₃₂N₂O₅
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Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
132388-59-1C₃₈H₃₂N₂O₅596.69 g/mol

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          Description
          Catalogue Number852044
          Replaces04-12-1089
          Brand Family Novabiochem®
          Alternate Names
          • N-α-Fmoc-N-β-trityl-L-asparagine
          Background InformationFmoc-Asn(Trt)-OH has good solubility properties in most organic solvents, and its use has been shown to result in significantly purer peptides than other derivatives used for the introduction of Asn [1, 2]. Coupling can be performed by standard procedures. The trityl group is normally removed by 95% TFA in 1-3 hours, with no alkylation of Trp residues. When Asn(Trt) is the N-terminal residue, the reaction time may need to be extended to ensure complete deprotection [3].

          The product number for this product was previously 04-12-1089.

          To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
          References
          Product Information
          CAS number132388-59-1
          Hill FormulaC₃₈H₃₂N₂O₅
          Molar Mass596.69 g/mol
          HS Code2924 29 99
          Structure formula ImageStructure formula Image
          Quality LevelMQ400
          Applications
          ApplicationFMOC-Asn(Trt)-OH N-α-Fmoc-N-ß-trityl-L-asparagine Novabiochem®. CAS 132388-59-1, molar mass 596.69 g/mol.
          Biological Information
          Physicochemical Information
          Melting Point220 °C
          pH value5.4 (H₂O, 23 °C)
          Solubility<0.00005 g/l
          Dimensions
          Materials Information
          Toxicological Information
          LD 50 oralLD50 Rat > 2000 mg/kg
          Safety Information according to GHS
          Hazard Pictogram(s) Hazard Pictogram(s)
          Hazard Statement(s)H411: Toxic to aquatic life with long lasting effects.
          Precautionary Statement(s)P273: Avoid release to the environment.
          P391: Collect spillage.
          P501: Dispose of contents/ container to an approved waste disposal plant.
          Storage class10 - 13 Other liquids and solids
          WGKWGK 2 obviously hazardous to water
          Safety Information
          Categories of dangerdangerous for the environment
          Product Usage Statements
          Storage and Shipping Information
          StorageStore at -15°C to -25°C.
          Packaging Information
          Transport Information
          Declaration (railroad and road) ADR, RIDUN 3077 , 9, III
          Declaration (transport by air) IATA-DGRUN 3077 , 9, III
          Declaration (transport by sea) IMDG-CodeUN 3077 , 9, III, Marine Pollutant: P
          Supplemental Information
          Specifications
          Color (visual)white to off white
          Appearance of substance (visual)powder
          Color index (0,5 M in DMF)≤ 150 Hazen
          Identity (IR)passes test
          Enantiomeric purity≥ 99.7 % (a/a)
          Purity (HPLC)≥ 99.0 % (a/a)
          Fmoc-ß-Ala-OH (HPLC)≤ 0.1 % (a/a)
          Fmoc-ß-Ala-Asn (Trt)-OH (HPLC)≤ 0.1 % (a/a)
          Fmoc-Asn(Trt)-Asn(Trt)-OH (HPLC)≤ 0.1 % (a/a)
          Fmoc-Asn-OH (HPLC)≤ 0.1 % (a/a)
          Assay free amino acid (GC)≤ 0.2 %
          Purity (TLC(011A))≥ 98 %
          Purity (TLC(0811))≥ 98 %
          Solubility (25 mmole in 50 ml DMF)clearly soluble
          Assay (acidimetric)≥ 98.0 %
          Water (K. F.)≤ 2.0 %
          Ethyl acetate (HS-GC)≤ 0.5 %
          Acetate (IC)≤ 0.05 %
          For TLC-Systems see our General Catalog
          Global Trade Item Number
          Catalogue Number GTIN
          8520440025 04027269086862
          8520440100 04027269086879

          Documentation

          FMOC-Asn(Trt)-OH SDS

          Title

          Safety Data Sheet (SDS) 

          Citations

          Title
          • [1] P. Sieber, et al. in 'Innovation & Perspectives in Solid Phase Synthesis, 1st International Symposium', R. Epton (Eds), SPCC UK Ltd., Birmingham, 1990, pp. 577.
          • [2] P. Sieber, et al. (1991) Tetrahedron Lett., 32, 739.
          • [3] M. Friede, et al. (1992) Pept. Res., 5, 145.