W431300
Hesperetin
≥95%
Synonym(s):
3′,5,7-Trihydroxy-4′-methoxyflavanone, 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-chromanone
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About This Item
Empirical Formula (Hill Notation):
C16H14O6
CAS Number:
Molecular Weight:
302.28
FEMA Number:
4313
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
16.097
NACRES:
NA.21
MDL number:
Organoleptic:
odorless
Biological source:
synthetic
Food allergen:
no known allergens
biological source
synthetic
assay
≥95%
form
powder (with a light tan cast)
mp
227-232 °C
application(s)
flavors and fragrances
documentation
see Safety & Documentation for available documents
food allergen
no known allergens
organoleptic
odorless
SMILES string
COc1ccc(cc1O)C2CC(=O)c3c(O)cc(O)cc3O2
InChI
1S/C16H14O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-6,14,17-19H,7H2,1H3
InChI key
AIONOLUJZLIMTK-UHFFFAOYSA-N
Disclaimer
For R&D or non-EU Food use. Not for retail sale.
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Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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Xuan Zeng et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1136, 121846-121846 (2019-12-11)
Naringin has been documented to possess multiple pharmacological activities. Reported pharmacokinetic studies revealed that oral bioavailability of naringin was low, in contrast to its significant pharmacological effects. The in vivo distribution of naringin and derived metabolites might partly explain this
Ramesh Elango et al.
Journal of Asian natural products research, 20(6), 559-569 (2017-05-26)
We studied the chemoprevention property of hesperetin on H522 cells using MTT, an apoptosis assay, an analysis of cell cycle progression, and the mitochondrial membrane potential, and apoptotic marker gene expression was determined using quantitative PCR. Hesperetin enhanced apoptotic cell
Elena Valeria Fuior et al.
Pharmaceutics, 11(8) (2019-08-07)
Citrus flavonoids have well-documented protective effects on cardiovascular system, but the poor water solubility and reduced bioavailability restrict their therapeutic use. We aimed to overcome these limitations and encapsulated naringenin and hesperetin into lipid nanoemulsions (LNs), targeted to vascular cell