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X6000

Xylometazoline hydrochloride

Synonym(s):

2-(4-tert-Butyl-2,6-dimethylbenzyl)-2-imidazoline hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C16H24N2 · HCl
CAS Number:
1218-35-5
Molecular Weight:
280.84
NACRES:
NA.77
PubChem Substance ID:
24278781
UNSPSC Code:
41116107
EC Number:
214-936-4
MDL number:
MFCD00238707
Quality level:
200
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Quality Level

200

originator

Novartis

SMILES string

CC1=CC(C(C)(C)C)=CC(C)=C1CC2=NCCN2.Cl

InChI

1S/C16H24N2.ClH/c1-11-8-13(16(3,4)5)9-12(2)14(11)10-15-17-6-7-18-15;/h8-9H,6-7,10H2,1-5H3,(H,17,18);1H

InChI key

YGWFCQYETHJKNX-UHFFFAOYSA-N

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)

Biochem/physiol Actions

α-adrenoceptor agonist; imidazoline binding site ligand.

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000323884
0000323884
SLCQ1434
SLBV8779
SLBT0203

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Catherine E Rennie et al.
International forum of allergy & rhinology, 1(2), 128-135 (2012-01-31)
This study quantifies the time-varying flow rate during inspiration at rest and in sniffing, both predecongestion and postdecongestion. It aims to provide a better understanding of nasal airflow mechanics, for application to the physiological modeling of nasal respiration and to
Jacek Sein Anand et al.
Przeglad lekarski, 66(6), 290-292 (2009-10-01)
The aim of our study was to present cases of misuse of different substances theoretically without abuse potential. In the last few years such behavior became an increasing problem in toxicological and emergency units. Lack of typical signs of intoxication
Katarzyna Korzeniowska et al.
Przeglad lekarski, 69(10), 1168-1169 (2013-02-21)
The article describes the case of 34-years old man, who has used nasal drops with xylomethazoline for three years. Health consequence of uncontrolled use of the drops and treatment were prescribed. Described problem confirms the need of physicians and pharmacists
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