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			96-Well Plate

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164606 Sigma-AldrichAminopeptidase N/CD13 Inhibitor - Calbiochem

The Aminopeptidase N/CD13 Inhibitor controls the biological activity of Aminopeptidase N/CD13. This small molecule/inhibitor is primarily used for Neuroscience applications.

Aminopeptidase N/CD13 Inhibitor - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: 4-tert-butylphenyl hydrogen 1-aminopropylphosphonate

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概述

Replacement Information

重要规格表

Empirical Formula
C₁₃H₂₂NO₃P

价格及供货情况

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Description
Overview	An alpha-aminoaralkylphosphonic acid ester that acts as an aminopeptidase N/CD13 inhibitor (IC₅₀=1.1 µM). Cell growth is dose dependently inhibited by as much as ~36% and ~60% in PANC-1 and HT-1080 cells, respectively when 300 µM of compound 4d is co-treated with 30 µg/ml of TNF. When treated with compound 4d alone, cell growth is dose-dependently inhibited by as much as 26% and 36%, in the same cell lines, respectively.
Catalogue Number	164606
Brand Family	Calbiochem®
Synonyms	4-tert-butylphenyl hydrogen 1-aminopropylphosphonate

References
References	Grzywa, R., et al. 2010. Bioorg. Med. Chem. 8, 2930.

Product Information
Form	White solid
Hill Formula	C₁₃H₂₂NO₃P
Chemical formula	C₁₃H₂₂NO₃P
Structure formula Image
Quality Level	MQ100

Applications

Biological Information
Purity	≥95% by HPLC

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Shipped with Blue Ice or with Dry Ice
Toxicity	Standard Handling
Storage	-20°C
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
164606-10MGCN	04055977207613

Documentation

Aminopeptidase N/CD13 Inhibitor - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Aminopeptidase N/CD13 Inhibitor - Calbiochem 分析证书

标题	批号
164606	输入批号

参考

参考信息概述
Grzywa, R., et al. 2010. Bioorg. Med. Chem. 8, 2930.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	16-April-2012 JSW
Synonyms	4-tert-butylphenyl hydrogen 1-aminopropylphosphonate
Description	An alpha-aminoaralkylphosphonic acid ester that acts as an aminopeptidase N/CD13 inhibitor (IC₅₀=1.1 µM). Cell growth is dose dependently inhibited by as much as ~36% and ~60% in PANC-1 and HT-1080 cells, respectively when 300 µM of compound 4d is co-treated with 30 µg/ml of TNF. When treated with compound 4d alone, cell growth is dose-dependently inhibited by as much as 26% and 36%, in the same cell lines, respectively.
Form	White solid
Chemical formula	C₁₃H₂₂NO₃P
Structure formula
Purity	≥95% by HPLC
Solubility	0.1N NaOH (1 mg/ml). Only partially soluble at 1 mg/ml in DMSO or H₂O.
Storage	-20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity	Standard Handling
References	Grzywa, R., et al. 2010. Bioorg. Med. Chem. 8, 2930.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Proteases Inhibitors

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