122262
N,N,N′,N′-Tetrakis(2-Hydroxypropyl)ethylenediamine
98%
Sinónimos:
Edetol, Entprol, (Ethylenedinitrilo)tetra-2-propanol, Quadrol®
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Fórmula lineal:
[CH3CH(OH)CH2]2NCH2CH2N[CH2CH(OH)CH3]2
Número CAS:
Peso molecular:
292.41
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
EC Number:
203-041-4
Beilstein/REAXYS Number:
1781143
MDL number:
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Permítanos ayudarlevapor pressure
1 mmHg ( 20 °C)
Quality Level
assay
98%
refractive index
n20/D 1.4812 (lit.)
bp
175-181 °C/0.8 mmHg (lit.)
density
1.013 g/mL at 25 °C (lit.)
SMILES string
CC(O)CN(CCN(CC(C)O)CC(C)O)CC(C)O
InChI
1S/C14H32N2O4/c1-11(17)7-15(8-12(2)18)5-6-16(9-13(3)19)10-14(4)20/h11-14,17-20H,5-10H2,1-4H3
InChI key
NSOXQYCFHDMMGV-UHFFFAOYSA-N
Categorías relacionadas
General description
N,N,N′,N′-Tetrakis(2-Hydroxypropyl)ethylenediamine (also known as Quadrol) is an ethylenediamine based monomer used in the production of polyurethane coatings, adhesives, cosmetics and personal care products. It can act as a chelating agent, due to the presence of its four hydroxyl groups, and a crosslinking agent, due to its two amino groups. It is widely used as a building block for polymers and copolymers, particularly those that are designed for use in UV-cross linkable polyurethane polymers, dendritic amino polymers, conducting polymers, inks, and coatings. Additionally, Quadrol is used in the production of resins, as well as in the manufacture of surfactants, plasticizers, and other chemical products.
Application
N,N,N′,N′-Tetrakis(2-Hydroxypropyl)ethylenediamine can be used as:
- A monomer in the synthesis of covalently cross-linked and amorphous shape memory polyurethane (SMPU) foams that are used in biomedical applications, which includes SMPU actuators for treating ischemic stroke, thrombus removal activated by laser light, self-deployable SMP neuronal electrodes, vascular stents, sutures in microsurgery, ocular implants, bandages, cell manipulation, and cell therapy.
- A precursor in the preparation of self-healing CFRPs (carbon fiber reinforced polymer) which are thermally responsive with excellent mechanical properties.
- A crosslinking agent to create a hydrogel that is biocompatible and supports the growth of neural cells. Hydrogels are specifically designed to mimic the properties of the extracellular matrix (ECM), in promoting cell proliferation. The purpose of the hydrogel in this context is to act as an extracellular matrix (ECM) substitute, providing a supportive environment for cell growth and guiding cell adhesion and outgrowth. This study investigates the potential of the peptide-modified channels to facilitate neural tissue engineering and enhance cell proliferation within the hydrogel-based scaffold.
Legal Information
Quadrol is a registered trademark of BASF Corporation
signalword
Warning
hcodes
pcodes
Hazard Classifications
Eye Irrit. 2
Clase de almacenamiento
10 - Combustible liquids
wgk
WGK 1
flash_point_f
411.8 °F - closed cup
flash_point_c
211 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves
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Histological analysis has been largely confined to two-dimensional analysis of thin tissue sections, hampering detailed understanding of three-dimensional cellular distribution in biological tissues. Tissue optical clearing methods enable three-dimensional histological analysis by rendering tissues transparent and suitable for microscopic detection
Low density biodegradable shape memory polyurethane foams for embolic biomedical applications
Pooja S, et al.
Acta Biomaterialia, 10(1), 67-76 (2014)
Thermally responsive self-healing composites with continuous carbon fiber reinforcement
Yunseon Heo and Henry A. Sodano
Composites Science and Technology, 118, 244-250 (2015)
Ona Gyliene et al.
Journal of hazardous materials, 171(1-3), 133-139 (2009-06-23)
The sorption by chitosan in Cu(II) solutions containing tartrate, glycine (amino acetic acid) and quadrol (N,N,N',N'-tetrakis(2-hydroxypropyl)ethylenediamine) as ligands has been investigated. The degree of sorbate removal strongly depends on pH. In solutions containing tartrate almost complete sorption of both Cu(II)
R Roure et al.
International journal of cosmetic science, 33(6), 519-526 (2011-05-14)
Three studies were performed to investigate the mechanism of action and evaluate the efficacy of a topical cosmetic slimming product combining tetrahydroxypropyl ethylenediamine, caffeine, carnitine, forskolin and retinol. The Ex vivo study on skin explants showed that caffeine and forskolin
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