HBTU

Name: HBTU
Brand: ALDRICH

≥98.0% (T), for peptide synthesis

Sinónimos:

N,N,N′,N′-Tetramethyl-O-(1H-benzotriazol-1-yl)uronium hexafluorophosphate, O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate

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About This Item

Fórmula empírica (notación de Hill):

C₁₁H₁₆F₆N₅OP

Número CAS:

94790-37-1

Peso molecular:

379.24

NACRES:

NA.22

PubChem Substance ID:

57647025

UNSPSC Code:

12352107

EC Number:

423-020-5

MDL number:

MFCD00075445

Beilstein/REAXYS Number:

7328329

Nombre del producto

HBTU, ≥98.0% (T)

InChI key

UQYZFNUUOSSNKT-UHFFFAOYSA-N

InChI

1S/C11H16N5O.F6P/c1-14(2)11(15(3)4)17-16-10-8-6-5-7-9(10)12-13-16;1-7(2,3,4,5)6/h5-8H,1-4H3;/q+1;-1

SMILES string

F[P-](F)(F)(F)(F)F.CN(C)C(\On1nnc2ccccc12)=[N+](/C)C

assay

≥98.0% (T)

form

solid

reaction suitability

reaction type: Coupling Reactions

mp

200 °C (dec.) (lit.)

solubility

acetonitrile: 0.1 g/mL, clear

application(s)

peptide synthesis

functional group

amine

storage temp.

2-8°C

Quality Level

200

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Categorías relacionadas

Amino Acids, Resins & Reagents for Peptide Synthesis

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Application

HBTU is a peptide coupling agent for peptide synthesis. It has also been used in standard Fmoc-based solid-phase peptide synthesis (SPPS) protocol.

Recent studies show that crystal as well as solution structure of this coupling agent is a guanidinium N-oxide and not an uronium compound; Coupling reagent for peptide synthesis; advantages are: very low racemization, simple reaction conditions, very short reaction time, and high yields.

General description

HBTU is a peptide coupling agent used in Fmoc-based solid-phase peptide synthesis.

pictograms

GHS07

signalword

Warning

hcodes

H317

pcodes

P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364

Hazard Classifications

Skin Sens. 1A

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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